Aging and the cardiac collagen matrix: Novel mediators of fibrotic remodelling

Por Horn, Margaux A., Trafford, Andrew W.
Publicado no J Mol Cell Cardiol (2016)

A model model: a commentary on DiFrancesco and Noble (1985) ‘A model of cardiac electrical activity incorporating ionic pumps and concentration changes’

Por Dibb, Katharine, Trafford, Andrew, Zhang, Henggui, Eisner, David
Publicado no Philos Trans R Soc Lond B Biol Sci (2015)

Calcium and Excitation-Contraction Coupling in the Heart

Por Eisner, David A., Caldwell, Jessica L., Kistamás, Kornél, Trafford, Andrew W.
Publicado no Circ Res (2017)

A computational model of spatio-temporal cardiac intracellular calcium handling with realistic structure and spatial flux distribution from sarcoplasmic reticulum and t-tubule reco...

Por Colman, Michael A., Pinali, Christian, Trafford, Andrew W., Zhang, Henggui, Kitmitto, Ashraf
Publicado no PLoS Comput Biol (2017)

Phosphodiesterase-5 inhibitors and the heart: compound cardioprotection?

Por Hutchings, David Charles, Anderson, Simon George, Caldwell, Jessica L, Trafford, Andrew W
Publicado no Heart (2018)

The Control of Diastolic Calcium in the Heart: Basic Mechanisms and Functional Implications

Por Eisner, David A., Caldwell, Jessica L., Trafford, Andrew W., Hutchings, David C.
Publicado no Circ Res (2020)

Direct measurements of SR free Ca reveal the mechanism underlying the transient effects of RyR potentiation under physiological conditions

Por Greensmith, David J., Galli, Gina L.J., Trafford, Andrew W., Eisner, David A.
Publicado em 2014

How does CaMKIIδ phosphorylation of the cardiac ryanodine receptor contribute to inotropy?

Por Eisner, David A., George, Christopher H., Smith, Godfrey L., Trafford, Andrew W., Venetucci, Luigi A.
Publicado em 2010

Balanced changes in Ca buffering by SERCA and troponin contribute to Ca handling during β-adrenergic stimulation in cardiac myocytes

Por Briston, Sarah J., Dibb, Katharine M., Solaro, R. John, Eisner, David A., Trafford, Andrew W.
Publicado no Cardiovasc Res (2014)

Human junctophilin-2 undergoes a structural rearrangement upon binding PtdIns(3,4,5)P(3) and the S101R mutation identified in hypertrophic cardiomyopathy obviates this response

Por Bennett, Hayley J., Davenport, John Bernard, Collins, Richard F., Trafford, Andrew W., Pinali, Christian, Kitmitto, Ashraf
Publicado em 2013

Localised micro-mechanical stiffening in the ageing aorta

Por Graham, Helen K., Akhtar, Riaz, Kridiotis, Constantinos, Derby, Brian, Kundu, Tribikram, Trafford, Andrew W., Sherratt, Michael J.
Publicado em 2011

Three-Dimensional Structure of the Intercalated Disc Reveals Plicate Domain and Gap Junction Remodeling in Heart Failure

Por Pinali, Christian, Bennett, Hayley J., Davenport, J. Bernard, Caldwell, Jessica L., Starborg, Tobias, Trafford, Andrew W., Kitmitto, Ashraf
Publicado no Biophys J (2015)

Increased Ca buffering underpins remodelling of Ca(2+) handling in old sheep atrial myocytes

Por Clarke, Jessica D., Caldwell, Jessica L., Pearman, Charles M., Eisner, David A., Trafford, Andrew W., Dibb, Katharine M.
Publicado no J Physiol (2017)

MAPS; acute safety data of the St Jude accent - tendril IPG system during prolonged max power CMR scanning

Por Ainslie, Mark P, Reid, Anna, Miller, Christopher A, Clark, David, Brown, Benjamin, Fox, David, Davidson, Neil, Trafford, Andrew, Schmitt, Matthias
Publicado no J Cardiovasc Magn Reson (2015)

Dependence of Cardiac Transverse Tubules on the BAR Domain Protein Amphiphysin II (BIN-1)

Por Caldwell, Jessica L., Smith, Charlotte E.R., Taylor, Rebecca F., Kitmitto, Ashraf, Eisner, David A., Dibb, Katharine M., Trafford, Andrew W.
Publicado no Circ Res (2014)

Postnatal enalapril to Improve Cardiovascular fUnction following preterm Preeclampsia (PICk-UP): a randomised double-blind placebo-controlled feasibility trial

Por Ormesher, Laura, Higson, Suzanne, Luckie, Matthew, Roberts, Stephen A, Glossop, Heather, Trafford, Andrew, Cottrell, Elizabeth, Johnstone, Edward D, Myers, Jenny E
Publicado no Hypertension (2020)

Calcium in the Pathophysiology of Atrial Fibrillation and Heart Failure

Por Denham, Nathan C., Pearman, Charles M., Caldwell, Jessica L., Madders, George W. P., Eisner, David A., Trafford, Andrew W., Dibb, Katharine M.
Publicado no Front Physiol (2018)

Chronic vagal nerve stimulation has no effect on tachycardia‐induced heart failure progression or excitation–contraction coupling

Por Radcliffe, Emma J., Pearman, Charles M., Watkins, Amy, Lawless, Michael, Kirkwood, Graeme J., Saxton, Sophie N., Eisner, David A., Trafford, Andrew W.
Publicado no Physiol Rep (2020)

Phosphodiesterase type-5 inhibitor use in type 2 diabetes is associated with a reduction in all-cause mortality

Por Anderson, Simon G, Hutchings, David C, Woodward, Mark, Rahimi, Kazem, Rutter, Martin K, Kirby, Mike, Hackett, Geoff, Trafford, Andrew W, Heald, Adrian H
Publicado no Heart (2016)

Non-ischemic Heart Preservation via Hypothermic Cardioplegic Perfusion Induces Immunodepletion of Donor Hearts Resulting in Diminished Graft Infiltration Following Transplantation

Por Critchley, William R., Stone, John P., Liao, Qiuming, Qin, Guangqi, Risnes, Ivar, Trafford, Andrew, Scott, Helge, Sjöberg, Trygve, Steen, Stig, Fildes, James E.
Publicado no Front Immunol (2020)