Impact of the Smoothened Inhibitor, IPI-926, on Smoothened Ciliary Localization and Hedgehog Pathway Activity

Por Peluso, Marisa O., Campbell, Veronica T., Harari, Joseph A., Tibbitts, Thomas T., Proctor, Jennifer L., Whitebread, Nigel, Conley, James M., White, Kerry F., Kutok, Jeffery L., Read, Margaret A., McGovern, Karen, Faia, Kerrie L.
Publicado em 2014

Discovery of a Selective Phosphoinositide-3-Kinase (PI3K)-γ Inhibitor (IPI-549) as an Immuno-Oncology Clinical Candidate

Por Evans, Catherine A., Liu, Tao, Lescarbeau, André, Nair, Somarajan J., Grenier, Louis, Pradeilles, Johan A., Glenadel, Quentin, Tibbitts, Thomas, Rowley, Ann M., DiNitto, Jonathan P., Brophy, Erin E., O’Hearn, Erin L., Ali, Janid A., Winkler, David G., Goldstein, Stanley I., O’Hearn, Patrick, Martin, Christian M., Hoyt, Jennifer G., Soglia, John R., Cheung, Culver, Pink, Melissa M., Proctor, Jennifer L., Palombella, Vito J., Tremblay, Martin R., Castro, Alfredo C.
Publicado no ACS Med Chem Lett (2016)