Role of cdc2 kinase phosphorylation and conserved N-terminal proteolysis motifs in cytoplasmic polyadenylation-element-binding protein (CPEB) complex dissociation and degradation.

por Thom, George, Minshall, Nicola, Git, Anna, Argasinska, Joanna, Standart, Nancy
Publicado 2003

Enhanced delivery of IL-1 receptor antagonist to the central nervous system as a novel anti–transferrin receptor-IL-1RA fusion reverses neuropathic mechanical hypersensitivity

por Webster, Carl I., Hatcher, Jon, Burrell, Matthew, Thom, George, Thornton, Peter, Gurrell, Ian, Chessell, Iain
Publicado en Pain (2016)

Modelling the endothelial blood-CNS barriers: a method for the production of robust in vitro models of the rat blood-brain barrier and blood-spinal cord barrier

por Watson, P Marc D, Paterson, Judy C, Thom, George, Ginman, Ulrika, Lundquist, Stefan, Webster, Carl I
Publicado 2013

Isolation of blood-brain barrier-crossing antibodies from a phage display library by competitive elution and their ability to penetrate the central nervous system

por Thom, George, Hatcher, Jon, Hearn, Arron, Paterson, Judy, Rodrigo, Natalia, Beljean, Arthur, Gurrell, Ian, Webster, Carl
Publicado en MAbs (2017)

Intracellular sorting and transcytosis of the rat transferrin receptor antibody OX26 across the blood–brain barrier in vitro is dependent on its binding affinity

por Haqqani, Arsalan S., Thom, George, Burrell, Matthew, Delaney, Christie E., Brunette, Eric, Baumann, Ewa, Sodja, Caroline, Jezierski, Anna, Webster, Carl, Stanimirovic, Danica B.
Publicado en J Neurochem (2018)

Validity of predictive equations to estimate RMR in females with varying BMI

por Thom, George, Gerasimidis, Konstantinos, Rizou, Eleni, Alfheeaid, Hani, Barwell, Nick, Manthou, Eirini, Fatima, Sadia, Gill, Jason M. R., Lean, Michael E. J., Malkova, Dalia
Publicado en J Nutr Sci (2020)

Validity of predictive equations to estimate RMR in females with varying BMI - CORRIGENDUM

por Thom, George, Gerasimidis, Konstantinos, Rizou, Eleni, Alfheeaid, Hani, Barwell, Nick, Manthou, Eirini, Fatima, Sadia, Gill, Jason M. R., Lean, Michael E. J., Malkova, Dalia
Publicado en J Nutr Sci (2020)

Probing a protein–protein interaction by in vitro evolution

por Thom, George, Cockroft, Alexis C., Buchanan, Andrew G., Joberty Candotti, Cathy, Cohen, E. Suzanne, Lowne, David, Monk, Phill, Shorrock-Hart, Celia P., Jermutus, Lutz, Minter, Ralph R.
Publicado 2006

A peptide derived from melanotransferrin delivers a protein-based interleukin 1 receptor antagonist across the BBB and ameliorates neuropathic pain in a preclinical model

por Thom, George, Tian, Mei-Mei, Hatcher, Jon P, Rodrigo, Natalia, Burrell, Matthew, Gurrell, Ian, Vitalis, Timothy Z, Abraham, Thomas, Jefferies, Wilfred A, Webster, Carl I, Gabathuler, Reinhard
Publicado en J Cereb Blood Flow Metab (2018)

Antibody-oligonucleotide conjugate achieves CNS delivery in animal models for spinal muscular atrophy

por Hammond, Suzan M., Abendroth, Frank, Goli, Larissa, Stoodley, Jessica, Burrell, Matthew, Thom, George, Gurrell, Ian, Ahlskog, Nina, Gait, Michael J., Wood, Matthew J.A., Webster, Carl I.
Publicado en JCI Insight (2022)

In vitro potency, pharmacokinetic profiles and pharmacological activity of optimized anti-IL-21R antibodies in a mouse model of lupus

por Vugmeyster, Yulia, Guay, Heath, Szklut, Pamela, Qian, Ming D, Jin, Macy, Widom, Angela, Spaulding, Vikki, Bennett, Frann, Lowe, Leslie, Andreyeva, Tatyana, Lowe, David, Lane, Steven, Thom, George, Valge-Archer, Viia, Gill, Davinder, Young, Deborah, Bloom, Laird
Publicado 2010

The Diabetes Remission Clinical Trial (DiRECT): protocol for a cluster randomised trial

por Leslie, Wilma S., Ford, Ian, Sattar, Naveed, Hollingsworth, Kieren G., Adamson, Ashley, Sniehotta, Falko F., McCombie, Louise, Brosnahan, Naomi, Ross, Hazel, Mathers, John C., Peters, Carl, Thom, George, Barnes, Alison, Kean, Sharon, McIlvenna, Yvonne, Rodrigues, Angela, Rehackova, Lucia, Zhyzhneuskaya, Sviatlana, Taylor, Roy, Lean, Mike E. J.
Publicado en BMC Fam Pract (2016)

Clinical and metabolic features of the randomised controlled Diabetes Remission Clinical Trial (DiRECT) cohort

por Taylor, Roy, Leslie, Wilma S., Barnes, Alison C, Brosnahan, Naomi, Thom, George, McCombie, Louise, Sattar, Naveed, Welsh, Paul, Peters, Carl, Zhyzhneuskaya, Sviatlana, Hollingsworth, Kieren G., Al-Mrabeh, Ahmad, Rodrigues, Angela M., Rehackova, Lucia, Adamson, Ashley J., Sniehotta, Falko F., Mathers, John C., Ross, Hazel M., McIlvenna, Yvonne, Kean, Sharon, Ford, Ian, McConnachie, Alex, Lean, Michael E. J.
Publicado en Diabetologia (2017)