Physical and Functional Analysis of the Putative Rpn13 Inhibitor RA190

Por Dickson, Paige, Abegg, Daniel, Vinogradova, Ekaterina, Takaya, Junichiro, An, Hongchan, Simanski, Scott, Cravatt, Benjamin F., Adibekian, Alexander, Kodadek, Thomas
Publicado no Cell Chem Biol (2020)

Small-molecule screening yields a compound that inhibits the cancer-associated transcription factor Hes1 via the PHB2 chaperone

Por Perron, Amelie, Nishikawa, Yoshihiro, Iwata, Jun, Shimojo, Hiromi, Takaya, Junichiro, Kobayashi, Kumiko, Imayoshi, Itaru, Mbenza, Naasson M., Takenoya, Mihoko, Kageyama, Ryoichiro, Kodama, Yuzo, Uesugi, Motonari
Publicado no J Biol Chem (2018)

Dimethyl fumarate disrupts human innate immune signaling by targeting the IRAK4-MYD88 complex

Por Zaro, Balyn W., Vinogradova, Ekaterina V., Lazar, Daniel C., Blewett, Megan M., Suciu, Radu M., Takaya, Junichiro, Studer, Sean, de la Torre, Juan Carlos, Casanova, Jean-Laurent, Cravatt, Benjamin F., Teijaro, John R.
Publicado no J Immunol (2019)