Novel Method for Probing the Specificity Binding Profile of Ligands: Applications to HIV Protease

Por Sherman, Woody, Tidor, Bruce
Publicado em 2008

Combined Model of Intrinsic and Extrinsic Variability for Computational Network Design with Application to Synthetic Biology

Por Toni, Tina, Tidor, Bruce
Publicado em 2013

Subsystem Identification Through Dimensionality Reduction of Large-Scale Gene Expression Data

Por Kim, Philip M., Tidor, Bruce
Publicado em 2003

Limitations of Quantitative Gene Regulation Models: A Case Study

Por Kim, Philip M., Tidor, Bruce
Publicado em 2003

Optimization of binding electrostatics: Charge complementarity in the barnase-barstar protein complex

Por lee, Lee-Peng, Tidor, Bruce
Publicado em 2001

MIST: Maximum Information Spanning Trees for dimension reduction of biological data sets

Por King, Bracken M., Tidor, Bruce
Publicado em 2009

Systematic placement of structural water molecules for improved scoring of protein–ligand interactions

Por Huggins, David J., Tidor, Bruce
Publicado em 2011

Specificity in Molecular Design: A Physical Framework for Probing the Determinants of Binding Specificity and Promiscuity in a Biological Environment

Por Radhakrishnan, Mala L., Tidor, Bruce
Publicado em 2007

Progress in Computational Protein Design

Por Lippow, Shaun M., Tidor, Bruce
Publicado em 2007

Computationally mapping sequence space to understand evolutionary protein engineering

Por Armstrong, Kathryn A., Tidor, Bruce
Publicado em 2007

Cellular Level Models as Tools for Cytokine Design

Por Radhakrishnan, Mala L., Tidor, Bruce
Publicado em 2010

Optimal Drug Cocktail Design: Methods for Targeting Molecular Ensembles and Insights From Theoretical Model Systems

Por Radhakrishnan, Mala L., Tidor, Bruce
Publicado em 2008

Modeling Stem Cell Induction Processes

Por Grácio, Filipe, Cabral, Joaquim, Tidor, Bruce
Publicado em 2013

Rational Approaches to Improving Selectivity in Drug Design

Por Huggins, David J., Sherman, Woody, Tidor, Bruce
Publicado em 2012

Charge Optimization Theory for Induced-Fit Ligands

Por Shen, Yang, Gilson, Michael K., Tidor, Bruce
Publicado em 2012

Molecular mechanisms and design principles for promiscuous inhibitors to avoid drug resistance: Lessons learned from HIV‐1 protease inhibition

Por Shen, Yang, Radhakrishnan, Mala L., Tidor, Bruce
Publicado no Proteins (2015)

The Per2 Negative Feedback Loop Sets the Period in the Mammalian Circadian Clock Mechanism

Por Wilkins, A. Katharina, Barton, Paul I, Tidor, Bruce
Publicado em 2007

A computational method for the analysis and prediction of protein:phosphopeptide-binding sites

Por Joughin, Brian A., Tidor, Bruce, Yaffe, Michael B.
Publicado em 2005

Action-at-a-distance interactions enhance protein binding affinity

Por Joughin, Brian A., Green, David F., Tidor, Bruce
Publicado em 2005

Evaluation of an Inverse Molecular Design Algorithm in a Model Binding Site

Por Huggins, David J., Altman, Michael D., Tidor, Bruce
Publicado em 2009