An innovative strategy for dual inhibitor design and its application in dual inhibition of human thymidylate synthase and dihydrofolate reductase enzymes.

Por Mahreen Arooj, Sugunadevi Sakkiah, Guang ping Cao, Keun Woo Lee
Publicado em 2013-01-01

A combination of receptor-based pharmacophore modeling & QM techniques for identification of human chymase inhibitors.

Por Mahreen Arooj, Sugunadevi Sakkiah, Songmi Kim, Venkatesh Arulalapperumal, Keun Woo Lee
Publicado em 2013-01-01

Identification of Important Chemical Features of 11β-Hydroxysteroid Dehydrogenase Type1 Inhibitors: Application of Ligand Based Virtual Screening and Density Functional Theory

Por Keun Woo Lee, Sundaraganesan Namadevan, Young-Sik Sohn, Chandrasekaran Meganathan, Sugunadevi Sakkiah
Publicado em 2012-04-01

Consensus Modeling for Prediction of Estrogenic Activity of Ingredients Commonly Used in Sunscreen Products

Por Huixiao Hong, Diego Rua, Sugunadevi Sakkiah, Chandrabose Selvaraj, Weigong Ge, Weida Tong
Publicado em 2016-09-01

Similarities and differences between variants called with human reference genome HG19 or HG38

Por Bohu Pan, Rebecca Kusko, Wenming Xiao, Yuanting Zheng, Zhichao Liu, Chunlin Xiao, Sugunadevi Sakkiah, Wenjing Guo, Ping Gong, Chaoyang Zhang, Weigong Ge, Leming Shi, Weida Tong, Huixiao Hong
Publicado em 2019-03-01

Ethanol Induced Disordering of Pancreatic Acinar Cell Endoplasmic Reticulum: An ER Stress/Defective Unfolded Protein Response ModelSummary

Por Richard T. Waldron, Hsin-Yuan Su, Honit Piplani, Joseph Capri, Whitaker Cohn, Julian P. Whitelegge, Kym F. Faull, Sugunadevi Sakkiah, Ravinder Abrol, Wei Yang, Bo Zhou, Michael R. Freeman, Stephen J. Pandol, Aurelia Lugea
Publicado em 2018-01-01

FOXC1 Activates Smoothened-Independent Hedgehog Signaling in Basal-like Breast Cancer

Por Bingchen Han, Ying Qu, Yanli Jin, Yi Yu, Nan Deng, Kolja Wawrowsky, Xiao Zhang, Na Li, Shikha Bose, Qiang Wang, Sugunadevi Sakkiah, Ravinder Abrol, Tor W. Jensen, Benjamin P. Berman, Hisashi Tanaka, Jeffrey Johnson, Bowen Gao, Jijun Hao, Zhenqiu Liu, Ralph Buttyan, Partha S. Ray, Mien-Chie Hung, Armando E. Giuliano, Xiaojiang Cui
Publicado em 2015-11-01