A Review of Imaging Agent Development

Por Agdeppa, Eric D., Spilker, Mary E.
Publicado em 2009

Metabolite and microbiome interplay in cancer immunotherapy

Por Johnson, Caroline H., Spilker, Mary E., Goetz, Laura, Peterson, Scott N., Siuzdak, Gary
Publicado no Cancer Res (2016)

Metabolomics activity screening for identifying metabolites that modulate phenotype

Por Guijas, Carlos, Montenegro-Burke, J Rafael, Warth, Benedikt, Spilker, Mary E, Siuzdak, Gary
Publicado no Nat Biotechnol (2018)

Predicting chemotherapy-induced neutropenia and granulocyte-colony stimulating factor response using model-based in vitro to clinical translation

Por Chen, Wenbo, Boras, Britton, Sung, Tae, Hu, Wenyue, Spilker, Mary E., D’Argenio, David Z.
Publicado no AAPS J (2020)

A whole‐body circulatory neutrophil model with application to predicting clinical neutropenia from in vitro studies

Por Chen, Wenbo, Boras, Britton, Sung, Tae, Hu, Wenyue, Spilker, Mary E., D’Argenio, David Z.
Publicado no CPT Pharmacometrics Syst Pharmacol (2021)

Comparison of Statistical Data Models for Identifying Differentially Expressed Genes Using a Generalized Likelihood Ratio Test

Por Seng, Kok-Yong, Glenny, Robb W., Madtes, David K., Spilker, Mary E., Vicini, Paolo, Gharib, Sina A.
Publicado em 2008

Automated identification of axonal growth cones in time-lapse image sequences

Por Keenan, Thomas M., Hooker, Andrew, Spilker, Mary E., Li, Nianzhen, Boggy, Gregory J., Vicini, Paolo, Folch, Albert
Publicado em 2005

A Physiological Model of Granulopoiesis to Predict Clinical Drug Induced Neutropenia from in vitro Bone Marrow Studies: With Application to a Cell Cycle Inhibitor

Por Chen, Wenbo, Boras, Britton, Sung, Tae, Yu, Yanke, Zheng, Jenny, Wang, Diane, Hu, Wenyue, Spilker, Mary E., D’Argenio, David Z.
Publicado no J Pharmacokinet Pharmacodyn (2020)

Assessment of near-infrared fluorophores to study the biodistribution and tumor targeting of an IL13 receptor α2 antibody by fluorescence molecular tomography

Por Gupta, Parul, Wentland, Jo-Ann, Leal, Mauricio, Ma, Dangshe, Roach, Rachel, Esparza, Antonio, King, Lindsay, Spilker, Mary E., Bagi, Cedo, Winkelmann, Christopher T., Giddabasappa, Anand
Publicado no Oncotarget (2017)

The development of a fully-integrated immune response model (FIRM) simulator of the immune response through integration of multiple subset models

Por Palsson, Sirus, Hickling, Timothy P, Bradshaw-Pierce, Erica L, Zager, Michael, Jooss, Karin, O’Brien, Peter J, Spilker, Mary E, Palsson, Bernhard O, Vicini, Paolo
Publicado em 2013

Monitoring metabolic responses to chemotherapy in single cells and tumors using nanostructure-initiator mass spectrometry (NIMS) imaging

Por O’Brien, Peter J, Lee, Michelle, Spilker, Mary E, Zhang, Cathy C, Yan, Zhengming, Nichols, Timothy C, Li, Wenlin, Johnson, Caroline H, Patti, Gary J, Siuzdak, Gary
Publicado em 2013

METLIN: A Technology Platform for Identifying Knowns and Unknowns

Por Guijas, Carlos, Montenegro-Burke, J. Rafael, Domingo-Almenara, Xavier, Palermo, Amelia, Warth, Benedikt, Hermann, Gerrit, Koellensperger, Gunda, Huan, Tao, Uritboonthai, Winnie, Aisporna, Aries E., Wolan, Dennis W., Spilker, Mary E., Benton, H. Paul, Siuzdak, Gary
Publicado no Anal Chem (2018)

Determining conserved metabolic biomarkers from a million database queries

Por Kurczy, Michael E., Ivanisevic, Julijana, Johnson, Caroline H., Uritboonthai, Winnie, Hoang, Linh, Fang, Mingliang, Hicks, Matthew, Aldebot, Anthony, Rinehart, Duane, Mellander, Lisa J., Tautenhahn, Ralf, Patti, Gary J., Spilker, Mary E., Benton, H. Paul, Siuzdak, Gary
Publicado no Bioinformatics (2015)

Applications of Quantitative Systems Pharmacology in Model‐Informed Drug Discovery: Perspective on Impact and Opportunities

Por Bradshaw, Erica L., Spilker, Mary E., Zang, Richard, Bansal, Loveleena, He, Handan, Jones, Rhys D.O., Le, Kha, Penney, Mark, Schuck, Edgar, Topp, Brian, Tsai, Alice, Xu, Christine, Nijsen, Marjoleen J.M.A., Chan, Jason R.
Publicado no CPT Pharmacometrics Syst Pharmacol (2019)

Preclinical QSP Modeling in the Pharmaceutical Industry: An IQ Consortium Survey Examining the Current Landscape

Por Nijsen, Marjoleen J.M.A., Wu, Fan, Bansal, Loveleena, Bradshaw‐Pierce, Erica, Chan, Jason R., Liederer, Bianca M., Mettetal, Jerome T., Schroeder, Patricia, Schuck, Edgar, Tsai, Alice, Xu, Christine, Chimalakonda, Anjaneya, Le, Kha, Penney, Mark, Topp, Brian, Yamada, Akihiro, Spilker, Mary E.
Publicado no CPT Pharmacometrics Syst Pharmacol (2018)

Comprehensive Bio-Imaging with Fluorinated Nanoparticles Using Breathable Liquids

Por Kurczy, Michael E., Zhu, Zheng Jiang, Ivanisevic, Julijana, Schuyler, Adam M., Lalwani, Kush, Santidrian, Antonio F., David, John W., Giddabasappa, Anand, Roberts, Amanda, Olivos, Hernando J., O'Brien, Peter J., Franco, Lauren, Fields, Matthew W., Paris, Liliana P., Friedlander, Martin, Johnson, Caroline H., Epstein, Adrian, Gendleman, Howard E., Wood, Malcolm, Felding-Habermann, Brunhilde, Patti, Gary J., Spilker, Mary E., Siuzdak, Gary
Publicado no Nat Commun (2015)

A novel CXCR4 antagonist IgG1 antibody (PF-06747143) for the treatment of hematologic malignancies

Por Liu, Shu-Hui, Gu, Yin, Pascual, Bernadette, Yan, Zhengming, Hallin, Max, Zhang, Cathy, Fan, Conglin, Wang, Wenlian, Lam, Justine, Spilker, Mary E., Yafawi, Rolla, Blasi, Eileen, Simmons, Brett, Huser, Nanni, Ho, Wei-Hsien, Lindquist, Kevin, Tran, Thomas-Toan, Kudaravalli, Jyothirmayee, Ma, Jing-Tyan, Jimenez, Gretchen, Barman, Ishita, Brown, Colleen, Chin, Sherman Michael, Costa, Maria J., Shelton, David, Smeal, Tod, Fantin, Valeria R., Pernasetti, Flavia
Publicado no Blood Adv (2017)