Molecular basis for specific viral RNA recognition and 2′-O-ribose methylation by the dengue virus nonstructural protein 5 (NS5)

Por Zhao, Yongqian, Soh, Tingjin Sherryl, Lim, Siew Pheng, Chung, Ka Yan, Swaminathan, Kunchithapadam, Vasudevan, Subhash G., Shi, Pei-Yong, Lescar, Julien, Luo, Dahai
Publicado no Proc Natl Acad Sci U S A (2015)

Flexibility of NS5 Methyltransferase-Polymerase Linker Region Is Essential for Dengue Virus Replication

Por Zhao, Yongqian, Soh, Tingjin Sherryl, Chan, Kitti Wing Ki, Fung, Sarah Suet Yin, Swaminathan, Kunchithapadam, Lim, Siew Pheng, Shi, Pei-Yong, Huber, Thomas, Lescar, Julien, Luo, Dahai, Vasudevan, Subhash G.
Publicado no J Virol (2015)

A Crystal Structure of the Dengue Virus NS5 Protein Reveals a Novel Inter-domain Interface Essential for Protein Flexibility and Virus Replication

Por Zhao, Yongqian, Soh, Tingjin Sherryl, Zheng, Jie, Chan, Kitti Wing Ki, Phoo, Wint Wint, Lee, Chin Chin, Tay, Moon Y. F., Swaminathan, Kunchithapadam, Cornvik, Tobias C., Lim, Siew Pheng, Shi, Pei-Yong, Lescar, Julien, Vasudevan, Subhash G., Luo, Dahai
Publicado no PLoS Pathog (2015)

Potent Allosteric Dengue Virus NS5 Polymerase Inhibitors: Mechanism of Action and Resistance Profiling

Por Lim, Siew Pheng, Noble, Christian Guy, Seh, Cheah Chen, Soh, Tingjin Sherryl, El Sahili, Abbas, Chan, Grace Kar Yarn, Lescar, Julien, Arora, Rishi, Benson, Timothy, Nilar, Shahul, Manjunatha, Ujjini, Wan, Kah Fei, Dong, Hongping, Xie, Xuping, Shi, Pei-Yong, Yokokawa, Fumiaki
Publicado no PLoS Pathog (2016)