Complement Evasion by Lyme Disease Spirochetes

by Skare, Jon T., Garcia, Brandon L.
Published in Trends Microbiol (2020)

The Classical Complement Pathway Is Required to Control Borrelia burgdorferi Levels During Experimental Infection

by Zhi, Hui, Xie, Jialei, Skare, Jon T.
Published in Front Immunol (2018)

The BB0646 protein demonstrates lipase and hemolytic activity associated with Borrelia burgdorferi, the aetiological agent of Lyme disease

by Shaw, Dana K., Hyde, Jenny A., Skare, Jon T.
Published 2011

Genetic Manipulation of Borrelia burgdorferi

by Hyde, Jenny A., Weening, Eric H., Skare, Jon T.
Published 2011

Live Imaging

by Chaconas, George, Moriarty, Tara J., Skare, Jon, Hyde, Jenny A.
Published in Curr Issues Mol Biol (2020)

Borrelia burgdorferi BBK32 Inhibits the Classical Pathway by Blocking Activation of the C1 Complement Complex

by Garcia, Brandon L., Zhi, Hui, Wager, Beau, Höök, Magnus, Skare, Jon T.
Published in PLoS Pathog (2016)

Invasion of Eukaryotic Cells by Borrelia burgdorferi Requires β(1) Integrins and Src Kinase Activity

by Wu, Jing, Weening, Eric H., Faske, Jennifer B., Höök, Magnus, Skare, Jon T.
Published 2011

BB0744 Affects Tissue Tropism and Spatial Distribution of Borrelia burgdorferi

by Wager, Beau, Shaw, Dana K., Groshong, Ashley M., Blevins, Jon S., Skare, Jon T.
Published in Infect Immun (2015)

Characterization of a Conditional bosR Mutant in Borrelia burgdorferi

by Hyde, Jenny A., Shaw, Dana K., Smith, Roger, Trzeciakowski, Jerome P., Skare, Jon T.
Published 2010

The BosR regulatory protein of Borrelia burgdorferi interfaces with the RpoS regulatory pathway and modulates both the oxidative stress response and pathogenic properties of the Ly...

by Hyde, Jenny A., Shaw, Dana K., Smith, Roger, Trzeciakowski, Jerome P., Skare, Jon T.
Published 2009

Analysis of Mechanisms Associated with Loss of Infectivity of Clonal Populations of Borrelia burgdorferi B31MI

by McDowell, John V., Sung, Shian Ying, Labandeira-Rey, Maria, Skare, Jon T., Marconi, Richard T.
Published 2001

Structural determination of the complement inhibitory domain of Borrelia burgdorferi BBK32 provides insight into classical pathway complement evasion by Lyme disease spirochetes

by Xie, Jialei, Zhi, Hui, Garrigues, Ryan J., Keightley, Andrew, Garcia, Brandon L., Skare, Jon T.
Published in PLoS Pathog (2019)

The BBA33 lipoprotein binds collagen and impacts Borrelia burgdorferi pathogenesis

by Zhi, Hui, Weening, Eric H., Barbu, Elena Magda, Hyde, Jenny A., Höök, Magnus, Skare, Jon T.
Published in Mol Microbiol (2015)

Lyme Disease Pathogenesis

by Coburn, Jenifer, Garcia, Brandon, Hu, Linden T., Jewett, Mollie W., Kraiczy, Peter, Norris, Steven J., Skare, Jon
Published in Curr Issues Mol Biol (2020)

Bioluminescent imaging of Borrelia burgdorferi in vivo demonstrates that the fibronectin binding protein BBK32 is required for optimal infectivity

by Hyde, Jenny A., Weening, Eric H., Chang, MiHee, Trzeciakowski, Jerome P., Höök, Magnus, Cirillo, Jeffrey D., Skare, Jon T.
Published 2011

The intergenic small non-coding RNA ittA is required for optimal infectivity and tissue tropism in Borrelia burgdorferi

by Medina-Pérez, Diana N., Wager, Beau, Troy, Erin, Gao, Lihui, Norris, Steven J., Lin, Tao, Hu, Linden, Hyde, Jenny A., Lybecker, Meghan, Skare, Jon T.
Published in PLoS Pathog (2020)

A high-throughput genetic screen identifies previously uncharacterized Borrelia burgdorferi genes important for resistance against reactive oxygen and nitrogen species

by Ramsey, Meghan E., Hyde, Jenny A., Medina-Perez, Diana N., Lin, Tao, Gao, Lihui, Lundt, Maureen E., Li, Xin, Norris, Steven J., Skare, Jon T., Hu, Linden T.
Published in PLoS Pathog (2017)

Genome-wide screen identifies novel genes required for Borrelia burgdorferi survival in its Ixodes tick vector

by Phelan, James P., Kern, Aurelie, Ramsey, Meghan E., Lundt, Maureen E., Sharma, Bijaya, Lin, Tao, Gao, Lihui, Norris, Steven J., Hyde, Jenny A., Skare, Jon T., Hu, Linden T.
Published in PLoS Pathog (2019)

Biomechanics of Borrelia burgdorferi Vascular Interactions

by Ebady, Rhodaba, Niddam, Alexandra F., Boczula, Anna E., Kim, Yae Ram, Gupta, Nupur, Tang, Tian Tian, Odisho, Tanya, Zhi, Hui, Simmons, Craig A., Skare, Jon T., Moriarty, Tara J.
Published in Cell Rep (2016)

Profiling of Temperature-Induced Changes in Borrelia burgdorferi Gene Expression by Using Whole Genome Arrays

by Ojaimi, Caroline, Brooks, Chad, Casjens, Sherwood, Rosa, Patricia, Elias, Abdallah, Barbour, Alan, Jasinskas, Algis, Benach, Jorge, Katona, Laura, Radolf, Justin, Caimano, Melissa, Skare, Jon, Swingle, Kristen, Akins, Darrin, Schwartz, Ira
Published 2003