Patient-derived stem cells: pathways to drug discovery for brain diseases

per Mackay-Sim, Alan
Publicat 2013

Hereditary Spastic Paraplegia: From Genes, Cells and Networks to Novel Pathways for Drug Discovery

per Mackay-Sim, Alan
Publicat a Brain Sci (2021)

Patient-Derived Stem Cell Models in SPAST HSP: Disease Modelling and Drug Discovery

per Wali, Gautam, Sue, Carolyn M., Mackay-Sim, Alan
Publicat a Brain Sci (2018)

Bitter Taste Transduction of Denatonium in the MudpuppyNecturus maculosus

per Ogura, Tatsuya, Mackay-Sim, Alan, Kinnamon, Sue C.
Publicat a J Neurosci (1997)

Leukaemia Inhibitory Factor Stimulates Proliferation of Olfactory Neuronal Progenitors via Inducible Nitric Oxide Synthase

per Lopez-Arenas, Estefania, Mackay-Sim, Alan, Bacigalupo, Juan, Sulz, Lorena
Publicat 2012

Schizophrenia patient-derived olfactory neurosphere-derived cells do not respond to extracellular reelin

per Tee, Jing Yang, Sutharsan, Ratneswary, Fan, Yongjun, Mackay-Sim, Alan
Publicat a NPJ Schizophr (2016)

Could Cells from Your Nose Fix Your Heart? Transplantation of Olfactory Stem Cells in a Rat Model of Cardiac Infarction

per McDonald, Cameron, Mackay-Sim, Alan, Crane, Denis, Murrell, Wayne
Publicat a ScientificWorldJournal (2010)

O1.5. SCHIZOPHRENIA PATIENT-DERIVED STEM CELLS FOR SYSTEMS GENOMICS: GENETIC VARIANTS, MOLECULAR PATHWAYS AND CELL FUNCTIONS ALTERED IN INDIVIDUAL PATIENTS

per Cristino, Alexandre, Tyebally, Mubarika, Sabdia, Muhammed, Thillaiyampalam, Gayathri, Mackay-Sim, Alan
Publicat a Schizophr Bull (2019)

Parkinson's disease-associated human ATP13A2 (PARK9) deficiency causes zinc dyshomeostasis and mitochondrial dysfunction

per Park, Jin-Sung, Koentjoro, Brianada, Veivers, David, Mackay-Sim, Alan, Sue, Carolyn M.
Publicat 2014

The comprehensive textbook of healthcare simulation

per Levine, Adam I., DeMaria Jr., Samuel., Schwartz, Andrew D., Sim, Alan J.
Publicat 2013.

Introduction of a hierarchy to LOINC to facilitate public health reporting.

per Steindel, Steven, Loonsk, John W., Sim, Alan, Doyle, Timothy J., Chapman, Robb S., Groseclose, Samuel L.
Publicat 2002

Mitochondrial Function in Hereditary Spastic Paraplegia: Deficits in SPG7 but Not SPAST Patient-Derived Stem Cells

per Wali, Gautam, Kumar, Kishore Raj, Liyanage, Erandhi, Davis, Ryan L., Mackay-Sim, Alan, Sue, Carolyn M.
Publicat a Front Neurosci (2020)

Transplantation of Neuronal-Primed Human Bone Marrow Mesenchymal Stem Cells in Hemiparkinsonian Rodents

per Khoo, Melissa L. M., Tao, Helen, Meedeniya, Adrian C. B., Mackay-Sim, Alan, Ma, David D. F.
Publicat 2011

Low dose tubulin-binding drugs rescue peroxisome trafficking deficit in patient-derived stem cells in Hereditary Spastic Paraplegia

per Fan, Yongjun, Wali, Gautam, Sutharsan, Ratneswary, Bellette, Bernadette, Crane, Denis I., Sue, Carolyn M., Mackay-Sim, Alan
Publicat 2014

Loss of Usp9x Disrupts Cortical Architecture, Hippocampal Development and TGFβ-Mediated Axonogenesis

per Stegeman, Shane, Jolly, Lachlan A., Premarathne, Susitha, Gecz, Jozef, Richards, Linda J., Mackay-Sim, Alan, Wood, Stephen A.
Publicat 2013

Oxidative Stress-Induced Axon Fragmentation Is a Consequence of Reduced Axonal Transport in Hereditary Spastic Paraplegia SPAST Patient Neurons

per Wali, Gautam, Liyanage, Erandhi, Blair, Nicholas F., Sutharsan, Ratneswary, Park, Jin-Sung, Mackay-Sim, Alan, Sue, Carolyn M.
Publicat a Front Neurosci (2020)

Variability in the Generation of Induced Pluripotent Stem Cells: Importance for Disease Modeling

per Vitale, Alejandra M., Matigian, Nicholas A., Ravishankar, Sugandha, Bellette, Bernadette, Wood, Stephen A., Wolvetang, Ernst J., Mackay-Sim, Alan
Publicat 2012

Mechanism of impaired microtubule-dependent peroxisome trafficking and oxidative stress in SPAST-mutated cells from patients with Hereditary Spastic Paraplegia

per Wali, Gautam, Sutharsan, Ratneswary, Fan, Yongjun, Stewart, Romal, Tello Velasquez, Johana, Sue, Carolyn M, Crane, Denis I., Mackay-Sim, Alan
Publicat a Sci Rep (2016)

Multipotent human stromal cells isolated from cord blood, term placenta and adult bone marrow show distinct differences in gene expression pattern

per Matigian, Nicholas, Brooke, Gary, Zaibak, Faten, Rossetti, Tony, Kollar, Katarina, Pelekanos, Rebecca, Heazlewood, Celena, Mackay-Sim, Alan, Wells, Christine A., Atkinson, Kerry
Publicat a Genom Data (2014)

A Cross-Study Transcriptional Analysis of Parkinson's Disease

per Sutherland, Greg T., Matigian, Nicholas A., Chalk, Alistair M., Anderson, Matthew J., Silburn, Peter A., Mackay-Sim, Alan, Wells, Christine A., Mellick, George D.
Publicat 2009