Synthesis of 3,6-bis[H-Tyr/H-Dmt-NH(CH(2))(m,n)]-2(1H)pyrazinone derivatives: function of alkyl chain length on opioid activity

Por Shiotani, Kimitaka, Li, Tingyou, Miyazaki, Anna, Tsuda, Yuko, Bryant, Sharon D., Ambo, Akihiro, Sasaki, Yusuke, Lazarus, Lawrence H., Okada, Yoshio
Publicado em 2006

Design and Synthesis of Opioidmimetics Containing 2′,6′-Dimethyl-l-tyrosine and a Pyrazinone-Ring Platform

Por Shiotani, Kimitaka, Li, Tingyou, Miyazaki, Anna, Tsuda, Yuko, Yokoi, Toshio, Ambo, Akihiro, Sasaki, Yusuke, Bryant, Sharon D., Lazarus, Lawrence H., Okada, Yoshio
Publicado em 2007

Bifunctional [2’,6’-Dimethyl-l-tyrosine(1)]Endomorphin-2 Analogues Substituted at Position 3 with Alkylated Phenylalanine Derivatives Yield Potent Mixed μ-Agonist/δ-Antagonist and...

Por Li, Tingyou, Shiotani, Kimitaka, Miyazaki, Anna, Tsuda, Yuko, Ambo, Akihiro, Sasaki, Yusuke, Jinsmaa, Yunden, Marczak, Ewa, Bryant, Sharon D., Lazarus, Lawrence H., Okada, Yoshio
Publicado em 2007