Epigenetic mechanisms regulating longevity and aging

le Sen, Payel, Shah, Parisha P., Nativio, Raffaella, Berger, Shelley L.
Foilsithe in Cell (2016)

Tid1/Rdh54 promotes dissociation of Dmc1 from nonrecombinogenic sites on meiotic chromatin

le Holzen, Teresa M., Shah, Parisha P., Olivares, Heidi A., Bishop, Douglas K.
Foilsithe 2006

Swi2/Snf2-related translocases prevent accumulation of toxic Rad51 complexes during mitotic growth

le Shah, Parisha P., Zheng, Xiuzhong, Epshtein, Anastasiya, Carey, Jeffrey N., Bishop, Douglas K., Klein, Hannah L.
Foilsithe 2010

H4K44 acetylation facilitates chromatin accessibility during meiosis

le Hu, Jialei, Donahue, Greg, Dorsey, Jean, Govin, Jérôme, Yuan, Zuofei, Garcia, Benjamin A., Shah, Parisha P., Berger, Shelley L.
Foilsithe in Cell Rep (2015)

A Balance Between Intermediate Filaments and Microtubules Maintains Nuclear Architecture in the Cardiomyocyte

le Heffler, Julie, Shah, Parisha P., Robison, Patrick, Phyo, Sai, Veliz, Kimberly, Uchida, Keita, Bogush, Alexey, Rhoades, Joshua, Jain, Rajan, Prosser, Benjamin L.
Foilsithe in Circ Res (2019)

Systematic genetic and proteomic screens during gametogenesis identify H2BK34 methylation as an evolutionary conserved meiotic mark

le Crespo, Marion, Luense, Lacey J., Arlotto, Marie, Hu, Jialei, Dorsey, Jean, García-Oliver, Encar, Shah, Parisha P., Pflieger, Delphine, Berger, Shelley L., Govin, Jérôme
Foilsithe in Epigenetics Chromatin (2020)

Core components of the nuclear pore bind distinct states of chromatin and contribute to Polycomb repression.

le Gozalo, Alejandro, Duke, Ashley, Lan, Yemin, Pascual-Garcia, Pau, Talamas, Jessica A., Nguyen, Son C., Shah, Parisha P., Jain, Rajan, Joyce, Eric F., Capelson, Maya
Foilsithe in Mol Cell (2019)

Lysosome-mediated processing of chromatin in senescence

le Ivanov, Andre, Pawlikowski, Jeff, Manoharan, Indrani, van Tuyn, John, Nelson, David M., Rai, Taranjit Singh, Shah, Parisha P., Hewitt, Graeme, Korolchuk, Viktor I., Passos, Joao F., Wu, Hong, Berger, Shelley L., Adams, Peter D.
Foilsithe 2013

Lamin B1 depletion in senescent cells triggers large-scale changes in gene expression and the chromatin landscape

le Shah, Parisha P., Donahue, Greg, Otte, Gabriel L., Capell, Brian C., Nelson, David M., Cao, Kajia, Aggarwala, Varun, Cruickshanks, Hazel A., Rai, Taranjit Singh, McBryan, Tony, Gregory, Brian D., Adams, Peter D., Berger, Shelley L.
Foilsithe 2013

MLL1 is essential for the senescence-associated secretory phenotype

le Capell, Brian C., Drake, Adam M., Zhu, Jiajun, Shah, Parisha P., Dou, Zhixun, Dorsey, Jean, Simola, Daniel F., Donahue, Greg, Sammons, Morgan, Rai, Taranjit Singh, Natale, Christopher, Ridky, Todd W., Adams, Peter D., Berger, Shelley L.
Foilsithe in Genes Dev (2016)

Senescent cells harbour features of the cancer epigenome

le Cruickshanks, Hazel A., McBryan, Tony, Nelson, David M., VanderKraats, Nathan D., Shah, Parisha P., van Tuyn, John, Rai, Taranjit Singh, Brock, Claire, Donahue, Greg, Dunican, Donncha S., Drotar, Mark E., Meehan, Richard R., Edwards, John R., Berger, Shelley L., Adams, Peter D.
Foilsithe 2013

Genome-nuclear lamina interactions regulate cardiac stem cell lineage restriction

le Poleshko, Andrey, Shah, Parisha P., Gupta, Mudit, Babu, Apoorva, Morley, Michael, Manderfield, Lauren J., Ifkovits, Jamie L., Calderon, Damelys, Aghajanian, Haig, Sierra-Pagán, Javier E., Sun, Zheng, Wang, Qiaohong, Li, Li, Dubois, Nicole, Morrisey, Edward E., Lazar, Mitchell A., Smith, Cheryl L., Epstein, Jonathan A., Jain, Rajan
Foilsithe in Cell (2017)

BRD4 Interacts with GATA4 to Govern Mitochondrial Homeostasis in Adult Cardiomyocytes

le Padmanabhan, Arun, Alexanian, Michael, Linares-Saldana, Ricardo, González-Terán, Bárbara, Andreoletti, Gaia, Huang, Yu, Connolly, Andrew J., Kim, Wonho, Hsu, Austin, Duan, Qiming, Winchester, Sarah A. B., Felix, Franco, Perez-Bermejo, Juan A., Wang, Qiaohong, Li, Li, Shah, Parisha P., Haldar, Saptarsi M., Jain, Rajan, Srivastava, Deepak
Foilsithe in Circulation (2020)

Autophagy mediates degradation of nuclear lamina

le Dou, Zhixun, Xu, Caiyue, Donahue, Greg, Shimi, Takeshi, Pan, Ji-An, Zhu, Jiajun, Ivanov, Andrejs, Capell, Brian C., Drake, Adam M., Shah, Parisha P., Catanzaro, Joseph M., Ricketts, M. Daniel, Lamark, Trond, Adam, Stephen A., Marmorstein, Ronen, Zong, Wei-Xing, Johansen, Terje, Goldman, Robert D., Adams, Peter D., Berger, Shelley L.
Foilsithe in Nature (2015)

Pathogenic LMNA variants disrupt cardiac lamina-chromatin interactions and de-repress alternative fate genes

le Shah, Parisha P., Lv, Wenjian, Rhoades, Joshua H., Poleshko, Andrey, Abbey, Deepti, Caporizzo, Matthew A., Linares-Saldana, Ricardo, Heffler, Julie G., Sayed, Nazish, Thomas, Dilip, Wang, Qiaohong, Stanton, Liam J., Bedi, Kenneth, Morley, Michael P., Cappola, Thomas P., Owens, Anjali T., Margulies, Kenneth B., Frank, David B., Wu, Joseph C., Rader, Daniel J., Yang, Wenli, Prosser, Benjamin L., Musunuru, Kiran, Jain, Rajan
Foilsithe in Cell Stem Cell (2021)