Epigenetic mechanisms regulating longevity and aging

por Sen, Payel, Shah, Parisha P., Nativio, Raffaella, Berger, Shelley L.
Publicado en Cell (2016)

Tid1/Rdh54 promotes dissociation of Dmc1 from nonrecombinogenic sites on meiotic chromatin

por Holzen, Teresa M., Shah, Parisha P., Olivares, Heidi A., Bishop, Douglas K.
Publicado 2006

Swi2/Snf2-related translocases prevent accumulation of toxic Rad51 complexes during mitotic growth

por Shah, Parisha P., Zheng, Xiuzhong, Epshtein, Anastasiya, Carey, Jeffrey N., Bishop, Douglas K., Klein, Hannah L.
Publicado 2010

H4K44 acetylation facilitates chromatin accessibility during meiosis

por Hu, Jialei, Donahue, Greg, Dorsey, Jean, Govin, Jérôme, Yuan, Zuofei, Garcia, Benjamin A., Shah, Parisha P., Berger, Shelley L.
Publicado en Cell Rep (2015)

A Balance Between Intermediate Filaments and Microtubules Maintains Nuclear Architecture in the Cardiomyocyte

por Heffler, Julie, Shah, Parisha P., Robison, Patrick, Phyo, Sai, Veliz, Kimberly, Uchida, Keita, Bogush, Alexey, Rhoades, Joshua, Jain, Rajan, Prosser, Benjamin L.
Publicado en Circ Res (2019)

Systematic genetic and proteomic screens during gametogenesis identify H2BK34 methylation as an evolutionary conserved meiotic mark

por Crespo, Marion, Luense, Lacey J., Arlotto, Marie, Hu, Jialei, Dorsey, Jean, García-Oliver, Encar, Shah, Parisha P., Pflieger, Delphine, Berger, Shelley L., Govin, Jérôme
Publicado en Epigenetics Chromatin (2020)

Core components of the nuclear pore bind distinct states of chromatin and contribute to Polycomb repression.

por Gozalo, Alejandro, Duke, Ashley, Lan, Yemin, Pascual-Garcia, Pau, Talamas, Jessica A., Nguyen, Son C., Shah, Parisha P., Jain, Rajan, Joyce, Eric F., Capelson, Maya
Publicado en Mol Cell (2019)

Lysosome-mediated processing of chromatin in senescence

por Ivanov, Andre, Pawlikowski, Jeff, Manoharan, Indrani, van Tuyn, John, Nelson, David M., Rai, Taranjit Singh, Shah, Parisha P., Hewitt, Graeme, Korolchuk, Viktor I., Passos, Joao F., Wu, Hong, Berger, Shelley L., Adams, Peter D.
Publicado 2013

Lamin B1 depletion in senescent cells triggers large-scale changes in gene expression and the chromatin landscape

por Shah, Parisha P., Donahue, Greg, Otte, Gabriel L., Capell, Brian C., Nelson, David M., Cao, Kajia, Aggarwala, Varun, Cruickshanks, Hazel A., Rai, Taranjit Singh, McBryan, Tony, Gregory, Brian D., Adams, Peter D., Berger, Shelley L.
Publicado 2013

MLL1 is essential for the senescence-associated secretory phenotype

por Capell, Brian C., Drake, Adam M., Zhu, Jiajun, Shah, Parisha P., Dou, Zhixun, Dorsey, Jean, Simola, Daniel F., Donahue, Greg, Sammons, Morgan, Rai, Taranjit Singh, Natale, Christopher, Ridky, Todd W., Adams, Peter D., Berger, Shelley L.
Publicado en Genes Dev (2016)

Senescent cells harbour features of the cancer epigenome

por Cruickshanks, Hazel A., McBryan, Tony, Nelson, David M., VanderKraats, Nathan D., Shah, Parisha P., van Tuyn, John, Rai, Taranjit Singh, Brock, Claire, Donahue, Greg, Dunican, Donncha S., Drotar, Mark E., Meehan, Richard R., Edwards, John R., Berger, Shelley L., Adams, Peter D.
Publicado 2013

Genome-nuclear lamina interactions regulate cardiac stem cell lineage restriction

por Poleshko, Andrey, Shah, Parisha P., Gupta, Mudit, Babu, Apoorva, Morley, Michael, Manderfield, Lauren J., Ifkovits, Jamie L., Calderon, Damelys, Aghajanian, Haig, Sierra-Pagán, Javier E., Sun, Zheng, Wang, Qiaohong, Li, Li, Dubois, Nicole, Morrisey, Edward E., Lazar, Mitchell A., Smith, Cheryl L., Epstein, Jonathan A., Jain, Rajan
Publicado en Cell (2017)

BRD4 Interacts with GATA4 to Govern Mitochondrial Homeostasis in Adult Cardiomyocytes

por Padmanabhan, Arun, Alexanian, Michael, Linares-Saldana, Ricardo, González-Terán, Bárbara, Andreoletti, Gaia, Huang, Yu, Connolly, Andrew J., Kim, Wonho, Hsu, Austin, Duan, Qiming, Winchester, Sarah A. B., Felix, Franco, Perez-Bermejo, Juan A., Wang, Qiaohong, Li, Li, Shah, Parisha P., Haldar, Saptarsi M., Jain, Rajan, Srivastava, Deepak
Publicado en Circulation (2020)

Autophagy mediates degradation of nuclear lamina

por Dou, Zhixun, Xu, Caiyue, Donahue, Greg, Shimi, Takeshi, Pan, Ji-An, Zhu, Jiajun, Ivanov, Andrejs, Capell, Brian C., Drake, Adam M., Shah, Parisha P., Catanzaro, Joseph M., Ricketts, M. Daniel, Lamark, Trond, Adam, Stephen A., Marmorstein, Ronen, Zong, Wei-Xing, Johansen, Terje, Goldman, Robert D., Adams, Peter D., Berger, Shelley L.
Publicado en Nature (2015)

Pathogenic LMNA variants disrupt cardiac lamina-chromatin interactions and de-repress alternative fate genes

por Shah, Parisha P., Lv, Wenjian, Rhoades, Joshua H., Poleshko, Andrey, Abbey, Deepti, Caporizzo, Matthew A., Linares-Saldana, Ricardo, Heffler, Julie G., Sayed, Nazish, Thomas, Dilip, Wang, Qiaohong, Stanton, Liam J., Bedi, Kenneth, Morley, Michael P., Cappola, Thomas P., Owens, Anjali T., Margulies, Kenneth B., Frank, David B., Wu, Joseph C., Rader, Daniel J., Yang, Wenli, Prosser, Benjamin L., Musunuru, Kiran, Jain, Rajan
Publicado en Cell Stem Cell (2021)