Optogenetic manipulation of cGMP in cells and animals by the tightly light-regulated guanylyl-cyclase opsin CyclOp

Por Gao, Shiqiang, Nagpal, Jatin, Schneider, Martin W., Kozjak-Pavlovic, Vera, Nagel, Georg, Gottschalk, Alexander
Publicado no Nat Commun (2015)

Engineered Cpf1 variants with altered PAM specificities increase genome targeting range

Por Gao, Linyi, Cox, David B.T., Yan, Winston X., Manteiga, John C., Schneider, Martin W., Yamano, Takashi, Nishimasu, Hiroshi, Nureki, Osamu, Crosetto, Nicola, Zhang, Feng
Publicado no Nat Biotechnol (2017)

BLISS is a versatile and quantitative method for genome-wide profiling of DNA double-strand breaks

Por Yan, Winston X., Mirzazadeh, Reza, Garnerone, Silvano, Scott, David, Schneider, Martin W., Kallas, Tomasz, Custodio, Joaquin, Wernersson, Erik, Li, Yinqing, Gao, Linyi, Federova, Yana, Zetsche, Bernd, Zhang, Feng, Bienko, Magda, Crosetto, Nicola
Publicado no Nat Commun (2017)