Brain perfusion and permeability in patients with advanced, refractory glioblastoma treated with lomustine and the transforming growth factor-β receptor I kinase inhibitor LY215729...

Por SEPULVEDA-SANCHEZ, JUAN, RAMOS, ANA, HILARIO, AMAYA, DE VELASCO, GUILLERMO, CASTELLANO, DANIEL, GARCIA DE LA TORRE, MARTA, RODON, JORDI, LAHN, MICHAEL F.
Publicado no Oncol Lett (2015)

Cardiac Safety of TGF-β Receptor I Kinase Inhibitor LY2157299 Monohydrate in Cancer Patients in a First-in-Human Dose Study

Por Kovacs, Richard J., Maldonado, Giuliana, Azaro, Analia, Fernández, Maria S., Romero, Federico L., Sepulveda-Sánchez, Juan M., Corretti, Mary, Carducci, Michael, Dolan, Melda, Gueorguieva, Ivelina, Cleverly, Ann L., Pillay, N. Sokalingum, Baselga, Jose, Lahn, Michael M.
Publicado no Cardiovasc Toxicol (2014)

Pharmacokinetic, pharmacodynamic and biomarker evaluation of transforming growth factor-β receptor I kinase inhibitor, galunisertib, in phase 1 study in patients with advanced canc...

Por Rodón, Jordi, Carducci, Michael, Sepulveda-Sánchez, Juan M., Azaro, Analía, Calvo, Emiliano, Seoane, Joan, Braña, Irene, Sicart, Elisabet, Gueorguieva, Ivelina, Cleverly, Ann, Pillay, N. Sokalingum, Desaiah, Durisala, Estrem, Shawn T., Paz-Ares, Luis, Holdhoff, Matthias, Blakeley, Jaishri, Lahn, Michael M., Baselga, Jose
Publicado no Invest New Drugs (2014)

First-in-Human Dose Study of the Novel Transforming Growth Factor-β Receptor I Kinase Inhibitor LY2157299 Monohydrate in Patients with Advanced Cancer and Glioma

Por Rodon, Jordi, Carducci, Michael A., Sepulveda-Sánchez, Juan M, Azaro, Analia, Calvo, Emiliano, Seoane, Joan, Braña, Irene, Sicart, Elisabet, Gueorguieva, Ivelina, Cleverly, Ann L., Pillay, N. Sokalingum, Desaiah, Durisala, Estrem, Shawn T., Paz-Ares, Luis, Holdhoff, Matthias, Blakeley, Jaishri, Lahn, Michael M., Baselga, Jose
Publicado no Clin Cancer Res (2014)

A Phase II randomized study of galunisertib monotherapy or galunisertib plus lomustine compared with lomustine monotherapy in patients with recurrent glioblastoma

Por Brandes, Alba A., Carpentier, Antoine F., Kesari, Santosh, Sepulveda-Sanchez, Juan M., Wheeler, Helen R., Chinot, Olivier, Cher, Lawrence, Steinbach, Joachim P., Capper, David, Specenier, Pol, Rodon, Jordi, Cleverly, Ann, Smith, Claire, Gueorguieva, Ivelina, Miles, Colin, Guba, Susan C., Desaiah, Durisala, Lahn, Michael M., Wick, Wolfgang
Publicado no Neuro Oncol (2016)