Wordt geladen...
Pharmacokinetic, pharmacodynamic and biomarker evaluation of transforming growth factor-β receptor I kinase inhibitor, galunisertib, in phase 1 study in patients with advanced cancer
Purpose Transforming growth factor-beta (TGF-β) signaling plays a key role in epithelial-mesenchymal transition (EMT) of tumors, including malignant glioma. Small molecule inhibitors (SMI) blocking TGF-β signaling reverse EMT and arrest tumor progression. Several SMIs were developed, but currently o...
Bewaard in:
| Gepubliceerd in: | Invest New Drugs |
|---|---|
| Hoofdauteurs: | , , , , , , , , , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Springer US
2014
|
| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4387272/ https://ncbi.nlm.nih.gov/pubmed/25529192 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-014-0192-4 |
| Tags: |
Voeg label toe
Geen labels, Wees de eerste die dit record labelt!
|