Troponin Regulatory Function and Dynamics Revealed by H/D Exchange-Mass Spectrometry

Por Kowlessur, Devanand, Tobacman, Larry S.
Publicado em 2010

Low Temperature Dynamic Mapping Reveals Unexpected Order and Disorder in Troponin

Por Kowlessur, Devanand, Tobacman, Larry S.
Publicado em 2010

Significance of Troponin Dynamics for Ca(2+)-mediated Regulation of Contraction and Inherited Cardiomyopathy

Por Kowlessur, Devanand, Tobacman, Larry S.
Publicado em 2012

Further studies of the role of Ser-16 in the regulation of the activity of phenylalanine hydroxylase.

Por Kowlessur, D, Yang, X J, Kaufman, S
Publicado em 1995

Characterization of the wild-type form of 4a-carbinolamine dehydratase and two naturally occurring mutants associated with hyperphenylalaninemia.

Por Johnen, G, Kowlessur, D, Citron, B A, Kaufman, S
Publicado em 1995

Mechanical Abnormalities of the Airway Wall in Adult Mice After Intrauterine Growth Restriction

Por Peter B. Noble, Darshinee Kowlessur, Darshinee Kowlessur, Alexander N. Larcombe, Alexander N. Larcombe, Graham M. Donovan, Kimberley C. W. Wang, Kimberley C. W. Wang
Publicado em 2019-08-01

A re-appraisal of the structural basis of stereochemical recognition in papain. Insensitivity of binding-site-catalytic-site signalling to P2-chirality in a time-dependent inhibiti...

Por Templeton, W, Kowlessur, D, Thomas, E W, Topham, C M, Brocklehurst, K
Publicado em 1990

Dependence of the P2-S2 stereochemical selectivity of papain on the nature of the catalytic-site chemistry. Quantification of selectivity in the catalysed hydrolysis of the enantio...

Por Kowlessur, D, Thomas, E W, Topham, C M, Templeton, W, Brocklehurst, K
Publicado em 1990

Catalytic-site characteristics of the porcine calpain II 80 kDa/18 kDa heterodimer revealed by selective reaction of its essential thiol group with two-hydronic-state time-dependen...

Por Mellor, G W, Sreedharan, S K, Kowlessur, D, Thomas, E W, Brocklehurst, K
Publicado em 1993

Differences in the chemical and catalytic characteristics of two crystallographically 'identical' enzyme catalytic sites. Characterization of actinidin and papain by a combination...

Por Salih, E, Malthouse, J P, Kowlessur, D, Jarvis, M, O'Driscoll, M, Brocklehurst, K
Publicado em 1987

Identification of signalling and non-signalling binding contributions to enzyme reactivity. Alternative combinations of binding interactions provide for change in transition-state...

Por Kowlessur, D, Topham, C M, Thomas, E W, O'Driscoll, M, Templeton, W, Brocklehurst, K
Publicado em 1989

The interplay of electrostatic fields and binding interactions determining catalytic-site reactivity in actinidin. A possible origin of differences in the behaviour of actinidin an...

Por Kowlessur, D, O'Driscoll, M, Topham, C M, Templeton, W, Thomas, E W, Brocklehurst, K
Publicado em 1989

A Role for Herpesvirus Entry Mediator as the Receptor for Herpes Simplex Virus 1 Entry into Primary Human Trabecular Meshwork Cells

Por Tiwari, Vaibhav, Clement, Christian, Scanlan, Perry M., Kowlessur, Devanand, Yue, Beatrice Y. J. T., Shukla, Deepak
Publicado em 2005

Structure of chymopapain M the late-eluted chymopapain deduced by comparative modelling techniques and active-centre characteristics determined by pH-dependent kinetics of catalysi...

Por Thomas, M P, Topham, C M, Kowlessur, D, Mellor, G W, Thomas, E W, Whitford, D, Brocklehurst, K
Publicado em 1994

Substrate-derived two-protonic-state electrophiles as sensitive kinetic specificity probes for cysteine proteinases. Activation of 2-pyridyl disulphides by hydrogen-bonding.

Por Brocklehurst, K, Kowlessur, D, O'Driscoll, M, Patel, G, Quenby, S, Salih, E, Templeton, W, Thomas, E W, Willenbrock, F
Publicado em 1987

Genetic influences on type 2 diabetes and metabolic syndrome related quantitative traits in Mauritius

Por Jowett, Jeremy B., Diego, Vincent P., Kotea, Navaratnam, Kowlessur, Sudhir, Chitson, Pierrot, Dyer, Thomas D., Zimmet, Paul, Blangero, John
Publicado em 2009

Genome-wide scan identifies a quantitative trait locus at 4p15.3 for serum urate

Por Cummings, Nik, Dyer, Thomas D, Kotea, Navaratnam, Kowlessur, Sudhir, Chitson, Pierrot, Zimmet, Paul, Blangero, John, Jowett, Jeremy B M
Publicado em 2010

High consumption of pulses is associated with lower risk of abnormal glucose metabolism in women in Mauritius

Por Wennberg, M., Söderberg, S., Uusitalo, U., Tuomilehto, J., Shaw, J. E., Zimmet, P. Z., Kowlessur, S., Pauvaday, V., Magliano, D. J.
Publicado no Diabet Med (2014)

The interplay of electrostatic and binding interactions determining active centre chemistry and catalytic activity in actinidin and papain.

Por Brocklehurst, K, O'Driscoll, M, Kowlessur, D, Phillips, I R, Templeton, W, Thomas, E W, Topham, C M, Wharton, C W
Publicado em 1989

Consequences of molecular recognition in the S1-S2 intersubsite region of papain for catalytic-site chemistry. Change in pH-dependence characteristics and generation of an inverse...

Por Brocklehurst, K, Kowlessur, D, Patel, G, Templeton, W, Quigley, K, Thomas, E W, Wharton, C W, Willenbrock, F, Szawelski, R J
Publicado em 1988