From GWAS to the clinic: risk factors for intracranial aneurysms

Por Ruigrok, Ynte M, Rinkel, Gabriel JE
Publicado em 2010

Genes influencing coagulation and the risk of aneurysmal subarachnoid hemorrhage, and subsequent complications of secondary cerebral ischemia and rebleeding

Por Ruigrok, Ynte M., Slooter, Arjen J. C., Rinkel, Gabriel J. E., Wijmenga, Cisca, Rosendaal, Frits R.
Publicado em 2009

Difference in Aneurysm Characteristics between Patients with Familial and Sporadic Aneurysmal Subarachnoid Haemorrhage

Por Mensing, Liselore A., Rinkel, Gabriel J. E., Vlak, Monique H. M., van der Schaaf, Irene C., Ruigrok, Ynte M.
Publicado no PLoS One (2016)

Circulating microRNAs in patients with intracranial aneurysms

Por Meeuwsen, John A. L., van ´t Hof, Femke N. G., van Rheenen, Wouter, Rinkel, Gabriel J. E., Veldink, Jan H., Ruigrok, Ynte M.
Publicado no PLoS One (2017)

A replication study of genetic risk loci for ischemic stroke in a Dutch population: a case-control study

Por Hauer, Allard J., Pulit, Sara L., van den Berg, Leonard H., de Bakker, Paul I. W., Veldink, Jan H., Ruigrok, Ynte M.
Publicado no Sci Rep (2017)

Whole Blood Gene Expression Profiles of Patients with a Past Aneurysmal Subarachnoid Hemorrhage

Por van ’t Hof, Femke N. G., Ruigrok, Ynte M., Medic, Jelena, Sanjabi, Bahram, van der Vlies, Pieter, Rinkel, Gabriel J. E., Veldink, Jan H.
Publicado no PLoS One (2015)

Long-term risk of aneurysmal subarachnoid hemorrhage after a negative aneurysm screen

Por Rasing, Ingeborg, Ruigrok, Ynte M., Greebe, Paut, Velthuis, Birgitta K., Witkamp, Theo D., Wermer, Marieke J.H., Roos, Yvo B., Vandertop, W. Peter, Rinkel, Gabriel J.E.
Publicado no Neurology (2015)

Age‐Specific Vascular Risk Factor Profiles According to Stroke Subtype

Por Hauer, Allard J., Ruigrok, Ynte M., Algra, Ale, van Dijk, Ewoud J., Koudstaal, Peter J., Luijckx, Gert‐Jan, Nederkoorn, Paul J., van Oostenbrugge, Robert J., Visser, Marieke C., Wermer, Marieke J., Kappelle, L. Jaap, Klijn, Catharina J. M.
Publicado no J Am Heart Assoc (2017)

Genetic variants associated with type 2 diabetes and adiposity and risk of intracranial and abdominal aortic aneurysms

Por van 't Hof, Femke NG, Vaucher, Julien, Holmes, Michael V, de Wilde, Arno, Baas, Annette F, Blankensteijn, Jan D, Hofman, Albert, Kiemeney, Lambertus ALM, Rivadeneira, Fernando, Uitterlinden, André G, Vermeulen, Sita H, Rinkel, Gabriël JE, de Bakker, Paul IW, Ruigrok, Ynte M
Publicado no Eur J Hum Genet (2017)

Evaluation of genetic risk loci for intracranial aneurysms in sporadic arteriovenous malformations of the brain

Por Kremer, Philip H. C., Koeleman, Bobby P. C., Pawlikowska, Ludmila, Weinsheimer, Shantel, Bendjilali, Nasrine, Sidney, Stephen, Zaroff, Jonathan G., Rinkel, Gabriel J. E., van den Berg, Leonard H., Ruigrok, Ynte M., de Kort, Gerard A. P., Veldink, Jan H., Kim, Helen, Klijn, Catharina J. M.
Publicado no J Neurol Neurosurg Psychiatry (2014)

Lessons Learned from Whole Exome Sequencing in Multiplex Families Affected by a Complex Genetic Disorder, Intracranial Aneurysm

Por Farlow, Janice L., Lin, Hai, Sauerbeck, Laura, Lai, Dongbing, Koller, Daniel L., Pugh, Elizabeth, Hetrick, Kurt, Ling, Hua, Kleinloog, Rachel, van der Vlies, Pieter, Deelen, Patrick, Swertz, Morris A., Verweij, Bon H., Regli, Luca, Rinkel, Gabriel J. E., Ruigrok, Ynte M., Doheny, Kimberly, Liu, Yunlong, Broderick, Joseph, Foroud, Tatiana
Publicado no PLoS One (2015)

Common variant near the endothelin receptor type A (EDNRA) gene is associated with intracranial aneurysm risk

Por Yasuno, Katsuhito, Bakırcıoğlu, Mehmet, Low, Siew-Kee, Bilgüvar, Kaya, Gaál, Emília, Ruigrok, Ynte M., Niemelä, Mika, Hata, Akira, Bijlenga, Philippe, Kasuya, Hidetoshi, Jääskeläinen, Juha E., Krex, Dietmar, Auburger, Georg, Simon, Matthias, Krischek, Boris, Ozturk, Ali K., Mane, Shrikant, Rinkel, Gabriel J. E., Steinmetz, Helmuth, Hernesniemi, Juha, Schaller, Karl, Zembutsu, Hitoshi, Inoue, Ituro, Palotie, Aarno, Cambien, François, Nakamura, Yusuke, Lifton, Richard P., Günel, Murat
Publicado em 2011

Recommendations from the International Stroke Genetics Consortium, Part 1: Standardized Phenotypic Data Collection

Por Majersik, Jennifer J., Cole, John W., Golledge, Jonathan, Rost, Natalia S., Yvonne Chan, Yu-Feng, Gurol, M. Edip, Lindgren, Arne G., Woo, Daniel, Fernandez-Cadenas, Israel, Chen, Donna T., Thijs, Vincent, Worrall, Bradford B, Kamal, Ayeesha, Bentley, Paul, Wardlaw, Joanna M, Ruigrok, Ynte M., Battey, Thomas W.K., Schmidt, Reinhold, Montaner, Joan, Giese, Anne-Katrin, Roquer, Jaume, Jiménez-Conde, Jordi, Lee, Chaeyoung, Ay, Hakan, Jose Martin, Juan, Rosand, Jonathan, Maguire, Jane
Publicado no Stroke (2014)

Interleukin-6 receptor pathways in abdominal aortic aneurysm

Por Harrison, Seamus C., Smith, Andrew J.P., Jones, Gregory T., Swerdlow, Daniel I., Rampuri, Riaz, Bown, Matthew J., Folkersen, Lasse, Baas, Annette F., de Borst, Gert Jan, Blankensteijn, Jan D., Price, Jacqueline F., van der Graaf, Yolanda, McLachlan, Stela, Agu, Obi, Hofman, Albert, Uitterlinden, Andre G., Franco-Cereceda, Anders, Ruigrok, Ynte M., van't Hof, F.N., Powell, Janet T., van Rij, Andre M., Casas, Juan P., Eriksson, Per, Holmes, Michael V., Asselbergs, Folkert W., Hingorani, Aroon D., Humphries, Steve E.
Publicado em 2013

Susceptibility loci for intracranial aneurysm in European and Japanese populations

Por Bilguvar, Kaya, Yasuno, Katsuhito, Niemelä, Mika, Ruigrok, Ynte M, von und zu Fraunberg, Mikael, van Duijn, Cornelia M, van den Berg, Leonard H, Mane, Shrikant, Mason, Christopher E, Choi, Murim, Gaál, Emília, Bayri, Yasar, Kolb, Luis, Arlier, Zulfikar, Ravuri, Sudhakar, Ronkainen, Antti, Tajima, Atsushi, Laakso, Aki, Hata, Akira, Kasuya, Hidetoshi, Koivisto, Timo, Rinne, Jaakko, Öhman, Juha, Breteler, Monique M B, Wijmenga, Cisca, State, Matthew W, Rinkel, Gabriel J E, Hernesniemi, Juha, Jääskeläinen, Juha E, Palotie, Aarno, Inoue, Ituro, Lifton, Richard P, Günel, Murat
Publicado em 2008

High Risk Population Isolate Reveals Low Frequency Variants Predisposing to Intracranial Aneurysms

Por Kurki, Mitja I., Gaál, Emília Ilona, Kettunen, Johannes, Lappalainen, Tuuli, Menelaou, Androniki, Anttila, Verneri, van 't Hof, Femke N. G., von und zu Fraunberg, Mikael, Helisalmi, Seppo, Hiltunen, Mikko, Lehto, Hanna, Laakso, Aki, Kivisaari, Riku, Koivisto, Timo, Ronkainen, Antti, Rinne, Jaakko, Kiemeney, Lambertus A. L., Vermeulen, Sita H., Kaunisto, Mari A., Eriksson, Johan G., Aromaa, Arpo, Perola, Markus, Lehtimäki, Terho, Raitakari, Olli T., Salomaa, Veikko, Gunel, Murat, Dermitzakis, Emmanouil T., Ruigrok, Ynte M., Rinkel, Gabriel J. E., Niemelä, Mika, Hernesniemi, Juha, Ripatti, Samuli, de Bakker, Paul I. W., Palotie, Aarno, Jääskeläinen, Juha E.
Publicado em 2014

GENOME-WIDE ASSOCIATION STUDY OF INTRACRANIAL ANEURYSM IDENTIFIES A NEW ASSOCIATION ON CHROMOSOME 7

Por Foroud, Tatiana, Lai, Dongbing, Koller, Daniel, van’t Hof, Femke, Kurki, Mitja I., Anderson, Craig S., Brown, Robert D., Connolly, E. Sander, Eriksson, Johan G., Flaherty, Matthew, Fornage, Myriam, von und zuFraunberg, Mikael, Gaál, Emília I., Laakso, Aki, Hernesniemi, Juha, Huston, John, Jääskeläinen, Juha E, Kiemeney, Lambertus A., Kivisaari, Riku, Kleindorfer, Dawn, Ko, Nerissa, Lehto, Hanna, Mackey, Jason, Meissner, Irene, Moomaw, Charles J., Mosley, Thomas H., Moskala, Marek, Niemelä, Mika, Palotie, Aarno, Pera, Joanna, Rinkel, Gabriel, Ripke, Stephan, Rouleau, Guy, Ruigrok, Ynte, Sauerbeck, Laura, Słowik, Agnieszka, Vermeulen, Sita H, Woo, Daniel, Worrall, Bradford B, Broderick, Joseph
Publicado em 2014

Genome-wide association study of intracranial aneurysm identifies three new risk loci

Por Yasuno, Katsuhito, Bilguvar, Kaya, Bijlenga, Philippe, Low, Siew Kee, Krischek, Boris, Auburger, Georg, Simon, Matthias, Krex, Dietmar, Arlier, Zulfikar, Nayak, Nikhil, Ruigrok, Ynte M, Niemela, Mika, Tajima, Atsushi, von und zu Fraunberg, Mikael, Doczi, Tamas, Wirjatijasa, Florentina, Hata, Akira, Blasco, Jordi, Oszvald, Agi, Kasuya, Hidetoshi, Zilani, Gulam, Schoch, Beate, Singh, Pankaj, Stüer, Carsten, Risselada, Roelof, Beck, Jürgen, Sola, Teresa, Ricciardi, Filomena, Aromaa, Arpo, Illig, Thomas, Schreiber, Stefan, van Duijn, Cornelia M, van den Berg, Leonard H, Perret, Claire, Proust, Carole, Roder, Constantin, Ozturk, Ali K, Gaál, Emília, Berg, Daniela, Geisen, Christof, Friedrich, Christoph M, Summers, Paul, Frangi, Alejandro F, State, Matthew W, Wichmann, HErich, Breteler, Monique M B, Wijmenga, Cisca, Mane, Shrikant, Peltonen, Leena, Elio, Vivas, Sturkenboom, Miriam CJM, Lawford, Patricia, Byrne, James, Macho, Juan, Sandalcioglu, Erol I, Meyer, Bernhard, Raabe, Andreas, Steinmetz, Helmuth, Rüfenacht, Daniel, Jääskeläinen, Juha E, Hernesniemi, Juha, Rinkel, Gabriel J E, Zembutsu, Hitoshi, Inoue, Ituro, Palotie, Aarno, Cambien, François, Nakamura, Yusuke, Lifton, Richard P, Günel, Murat
Publicado em 2010

Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm

Por Gretarsdottir, Solveig, Baas, Annette F, Thorleifsson, Gudmar, Holm, Hilma, den Heijer, Martin, de Vries, Jean-Paul P M, Kranendonk, Steef E, Zeebregts, Clark J A M, van Sterkenburg, Steven M, Geelkerken, Robert H, van Rij, Andre M, Williams, Michael J A, Boll, Albert P M, Kostic, Jelena P, Jonasdottir, Adalbjorg, Jonasdottir, Aslaug, Walters, G Bragi, Masson, Gisli, Sulem, Patrick, Saemundsdottir, Jona, Mouy, Magali, Magnusson, Kristinn P, Tromp, Gerard, Elmore, James R, Sakalihasan, Natzi, Limet, Raymond, Defraigne, Jean-Olivier, Ferrell, Robert E, Ronkainen, Antti, Ruigrok, Ynte M, Wijmenga, Cisca, Grobbee, Diederick E, Shah, Svati H, Granger, Christopher B, Quyyumi, Arshed A, Vaccarino, Viola, Patel, Riyaz S, Zafari, A Maziar, Levey, Allan I, Austin, Harland, Girelli, Domenico, Pignatti, Pier Franco, Olivieri, Oliviero, Martinelli, Nicola, Malerba, Giovanni, Trabetti, Elisabetta, Becker, Lewis C, Becker, Diane M, Reilly, Muredach P, Rader, Daniel J, Mueller, Thomas, Dieplinger, Benjamin, Haltmayer, Meinhard, Urbonavicius, Sigitas, Lindblad, Bengt, Gottsäter, Anders, Gaetani, Eleonora, Pola, Roberto, Wells, Philip, Rodger, Marc, Forgie, Melissa, Langlois, Nicole, Corral, Javier, Vicente, Vicente, Fontcuberta, Jordi, España, Francisco, Grarup, Niels, Jørgensen, Torben, Witte, Daniel R, Hansen, Torben, Pedersen, Oluf, Aben, Katja K, de Graaf, Jacqueline, Holewijn, Suzanne, Folkersen, Lasse, Franco-Cereceda, Anders, Eriksson, Per, Collier, David A, Stefansson, Hreinn, Steinthorsdottir, Valgerdur, Rafnar, Thorunn, Valdimarsson, Einar M, Magnadottir, Hulda B, Sveinbjornsdottir, Sigurlaug, Olafsson, Isleifur, Magnusson, Magnus Karl, Palmason, Robert, Haraldsdottir, Vilhelmina, Andersen, Karl, Onundarson, Pall T, Thorgeirsson, Gudmundur, Kiemeney, Lambertus A, Powell, Janet T, Carey, David J, Kuivaniemi, Helena, Lindholt, Jes S, Jones, Gregory T, Kong, Augustine, Blankensteijn, Jan D, Matthiasson, Stefan E, Thorsteinsdottir, Unnur, Stefansson, Kari
Publicado em 2010

Shared Genetic Risk Factors of Intracranial, Abdominal, and Thoracic Aneurysms

Por van ’t Hof, Femke N. G., Ruigrok, Ynte M., Lee, Cue Hyunkyu, Ripke, Stephan, Anderson, Graig, de Andrade, Mariza, Baas, Annette F., Blankensteijn, Jan D., Böttinger, Erwin P., Bown, Matthew J., Broderick, Joseph, Bijlenga, Philippe, Carrell, David S., Crawford, Dana C., Crosslin, David R., Ebeling, Christian, Eriksson, Johan G., Fornage, Myriam, Foroud, Tatiana, von und zu Fraunberg, Mikael, Friedrich, Christoph M., Gaál, Emília I., Gottesman, Omri, Guo, Dong‐Chuan, Harrison, Seamus C., Hernesniemi, Juha, Hofman, Albert, Inoue, Ituro, Jääskeläinen, Juha E., Jones, Gregory T., Kiemeney, Lambertus A. L. M., Kivisaari, Riku, Ko, Nerissa, Koskinen, Seppo, Kubo, Michiaki, Kullo, Iftikhar J., Kuivaniemi, Helena, Kurki, Mitja I., Laakso, Aki, Lai, Dongbing, Leal, Suzanne M., Lehto, Hanna, LeMaire, Scott A., Low, Siew‐Kee, Malinowski, Jennifer, McCarty, Catherine A., Milewicz, Dianna M., Mosley, Thomas H., Nakamura, Yusuke, Nakaoka, Hirofumi, Niemelä, Mika, Pacheco, Jennifer, Peissig, Peggy L., Pera, Joanna, Rasmussen‐Torvik, Laura, Ritchie, Marylyn D., Rivadeneira, Fernando, van Rij, Andre M., Santos‐Cortez, Regie Lyn P., Saratzis, Athanasios, Slowik, Agnieszka, Takahashi, Atsushi, Tromp, Gerard, Uitterlinden, André G., Verma, Shefali S., Vermeulen, Sita H., Wang, Gao T., Han, Buhm, Rinkel, Gabriël J. E., de Bakker, Paul I. W., Bown, Matthew J., Harrison, Seamus C., Saratzis, Athanasios, Verissimo, Ana, Wright, Benjamin J., Bumpstead, Suzannah, Baas, Annette F., Gretarsdottir, Solveig, Badger, Stephen A., Child, Anne H., Clough, Rachel E., Cockerill, Gillian, Hafez, Hany, Scott, D. Julian A., Futers, Simon, Sohrabi, Soroush, Smith, Alberto, Thompson, Matthew M., van Bockxmeer, Frank M., Matthiasson, Stefan E., Thorleifsson, Gudmar, Thorsteinsdottir, Unnur, Blankensteijn, Jan D., Teijink, Joep A. W., Wijmenga, Cisca, de Graaf, Jacqueline, Kiemeney, Lambertus A., Palmen, Jutta, Smith, Andrew J., Lindholt, Jes S., Bradley, Declan T., Waltham, Matthew, Edkins, Sarah, Gwilliam, Rhian, Hunt, Sarah E., Potter, Simon, Golledge, Jonathan, Eriksson, Per, Norman, Paul E., Powell, Janet T., Stefansson, Kari, Thompson, John R., Humphries, Steve E., Sayers, Robert D., Deloukas, Panos, Samani, Nilesh J., Jones, Gregory T., Phillip, L. Victoria, van Rij, Andre M., Hill, Geraldine B., Williams, Michael J. A., Thomson, Ian A., Krysa, Jo, Wilkins, Gerard T., Merriman, Tony R., Vasudevan, Thodor M., Lewis, David R., Blair, Ross D., Hill, Andrew A.
Publicado no J Am Heart Assoc (2016)