The t(12;21) translocation converts AML-1B from an activator to a repressor of transcription.

Por Hiebert, S W, Sun, W, Davis, J N, Golub, T, Shurtleff, S, Buijs, A, Downing, J R, Grosveld, G, Roussell, M F, Gilliland, D G, Lenny, N, Meyers, S
Publicado em 1996