Cellular basis of drug-induced torsades de pointes

le Roden, D M
Foilsithe 2008

Global parameter optimization for cardiac potassium channel gating models.

le Balser, J R, Roden, D M, Bennett, P B
Foilsithe 1990

Single inward rectifier potassium channels in guinea pig ventricular myocytes. Effects of quinidine.

le Balser, J R, Roden, D M, Bennett, P B
Foilsithe 1991

Mechanism of block of a human cardiac potassium channel by terfenadine racemate and enantiomers.

le Yang, T., Prakash, C., Roden, D. M., Snyders, D. J.
Foilsithe 1995

Stereoselective genetically-determined interaction between chronic flecainide and quinidine in patients with arrhythmias.

le Birgersdotter, U M, Wong, W, Turgeon, J, Roden, D M
Foilsithe 1992

Phenotypic debrisoquine 4-hydroxylase activity among extensive metabolizers is unrelated to genotype as determined by the Xba-I restriction fragment length polymorphism.

le Turgeon, J, Evans, W E, Relling, M V, Wilkinson, G R, Roden, D M
Foilsithe 1991

Genetically-determined interaction between propafenone and low dose quinidine: role of active metabolites in modulating net drug effect.

le Funck-Brentano, C, Kroemer, H K, Pavlou, H, Woosley, R L, Roden, D M
Foilsithe 1989

A mechanism of D-(+)-sotalol effects on heart rate not related to beta-adrenoceptor antagonism.

le Funck-Brentano, C, Silberstein, D J, Roden, D M, Wood, A J, Woosley, R L
Foilsithe 1990

The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors.

le Kim, R B, Fromm, M F, Wandel, C, Leake, B, Wood, A J, Roden, D M, Wilkinson, G R
Foilsithe 1998

Encainide and its metabolites. Comparative effects in man on ventricular arrhythmia and electrocardiographic intervals.

le Carey, E L, Duff, H J, Roden, D M, Primm, R K, Wilkinson, G R, Wang, T, Oates, J A, Woosley, R L
Foilsithe 1984

Indications for different modes of surgical therapy in medically refractory ventricular arrhythmias.

le Hammon, J W, Echt, D S, Merrill, W H, Primm, K R, Woosley, R L, Smith, R F, Roden, D M, Bender, H W
Foilsithe 1986

Suppression of ventricular arrhythmias in man by d-propranolol independent of beta-adrenergic receptor blockade.

le Murray, K T, Reilly, C, Koshakji, R P, Roden, D M, Lineberry, M D, Wood, A J, Siddoway, L A, Barbey, J T, Woosley, R L
Foilsithe 1990

Clinical Pharmacogenetics Implementation Consortium Guidelines for CYP2C19 Genotype and Clopidogrel Therapy: 2013 Update

le Scott, S A, Sangkuhl, K, Stein, C M, Hulot, J-S, Mega, J L, Roden, D M, Klein, T E, Sabatine, M S, Johnson, J A, Shuldiner, A R
Foilsithe 2013

The Clinical Pharmacogenetics Implementation Consortium Guideline for SLCO1B1 and Simvastatin-Induced Myopathy: 2014 Update

le Ramsey, L B, Johnson, S G, Caudle, K E, Haidar, C E, Voora, D, Wilke, R A, Maxwell, W D, McLeod, H L, Krauss, R M, Roden, D M, Feng, Q, Cooper-DeHoff, R M, Gong, L, Klein, T E, Wadelius, M, Niemi, M
Foilsithe 2014

A genome-wide association study identifies variants in KCNIP4 associated with ACE inhibitor-induced cough

le Mosley, J D, Shaffer, C M, Van Driest, S L, Weeke, P E, Wells, Q S, Karnes, J H, Velez Edwards, D R, Wei, W-Q, Teixeira, P L, Bastarache, L, Crawford, D C, Li, R, Manolio, T A, Bottinger, E P, McCarty, C A, Linneman, J G, Brilliant, M H, Pacheco, J A, Thompson, W, Chisholm, R L, Jarvik, G P, Crosslin, D R, Carrell, D S, Baldwin, E, Ralston, J, Larson, E B, Grafton, J, Scrol, A, Jouni, H, Kullo, I J, Tromp, G, Borthwick, K M, Kuivaniemi, H, Carey, D J, Ritchie, M D, Bradford, Y, Verma, S S, Chute, C G, Veluchamy, A, Siddiqui, M K, Palmer, C N A, Doney, A, MahmoudPour, S H, Maitland-van der Zee, A H, Morris, A D, Denny, J C, Roden, D M
Foilsithe in Pharmacogenomics J (2016)