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Encainide and its metabolites. Comparative effects in man on ventricular arrhythmia and electrocardiographic intervals.

To assess the relative contributions of encainide and its putatively active metabolites, O-demethyl encainide (ODE) and 3 methoxy-O-demethyl encainide (3MODE), to the drug's pharmacologic effects, we compared intravenous infusions and sustained oral therapy in two phenotypically distinct groups of p...

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Pubblicato in:J Clin Invest
Autori principali: Carey, E L, Duff, H J, Roden, D M, Primm, R K, Wilkinson, G R, Wang, T, Oates, J A, Woosley, R L
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1984
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC425046/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6421879/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI111241
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