FUCCI Real-Time Cell-Cycle Imaging as a Guide for Designing Improved Cancer Therapy: A Review of Innovative Strategies to Target Quiescent Chemo-Resistant Cancer Cells

Por Shuya Yano, Hiroshi Tazawa, Shunsuke Kagawa, Toshiyoshi Fujiwara, Robert M. Hoffman
Publicado em 2020-09-01

Comparison of efficacy and toxicity of traditional Chinese medicine (TCM) herbal mixture LQ and conventional chemotherapy on lung cancer metastasis and survival in mouse models.

Por Lei Zhang, Chengyu Wu, Yong Zhang, Fang Liu, Xiaoen Wang, Ming Zhao, Robert M Hoffman
Publicado em 2014-01-01

MUC1 selectively targets human pancreatic cancer in orthotopic nude mouse models.

Por Jeong Youp Park, Yukihiko Hiroshima, Jin Young Lee, Ali A Maawy, Robert M Hoffman, Michael Bouvet
Publicado em 2015-01-01

Myc is a prognostic biomarker and potential therapeutic target in osteosarcoma

Por Wenlong Feng, Dylan C. Dean, Francis J. Hornicek, Dimitrios Spentzos, Robert M. Hoffman, Huirong Shi, Zhenfeng Duan
Publicado em 2020-05-01

Near infra-red photoimmunotherapy with anti-CEA-IR700 results in extensive tumor lysis and a significant decrease in tumor burden in orthotopic mouse models of pancreatic cancer.

Por Ali A Maawy, Yukihiko Hiroshima, Yong Zhang, Roger Heim, Lew Makings, Miguel Garcia-Guzman, George A Luiken, Hisataka Kobayashi, Robert M Hoffman, Michael Bouvet
Publicado em 2015-01-01

Osimertinib regressed an EGFR-mutant lung-adenocarcinoma bone-metastasis mouse model and increased long-term survival

Por Takashi Higuchi, Norihiko Sugisawa, Jun Ho Park, Yu Sun, Guangwei Zhu, Norio Yamamoto, Katsuhiro Hayashi, Hiroaki Kimura, Shinji Miwa, Kentaro Igarashi, Michael Bouvet, Shree Ram Singh, Hiroyuki Tsuchiya, Robert M. Hoffman
Publicado em 2020-10-01

The tumor-educated-macrophage increase of malignancy of human pancreatic cancer is prevented by zoledronic acid.

Por Yukihiko Hiroshima, Ali Maawy, Mohamed K Hassanein, Rhiana Menen, Masashi Momiyama, Takashi Murakami, Shinji Miwa, Mako Yamamoto, Fuminari Uehara, Shuya Yano, Ryutaro Mori, Ryusei Matsuyama, Takashi Chishima, Kuniya Tanaka, Yasushi Ichikawa, Michael Bouvet, Itaru Endo, Robert M Hoffman
Publicado em 2014-01-01

Tumor-targeting Salmonella typhimurium A1-R suppressed an imatinib-resistant gastrointestinal stromal tumor with c-kit exon 11 and 17 mutations

Por Kentaro Miyake, Kei Kawaguchi, Masuyo Miyake, Ming Zhao, Tasuku Kiyuna, Kentaro Igarashi, Zhiying Zhang, Takashi Murakami, Yunfeng Li, Scott D. Nelson, Michael Bouvet, Irmina Elliott, Tara A. Russell, Arun S. Singh, Yukihiko Hiroshima, Masashi Momiyama, Ryusei Matsuyama, Takashi Chishima, Shree Ram Singh, Itaru Endo, Fritz C. Eilber, Robert M. Hoffman
Publicado em 2018-06-01