Phenome-Wide Association Studies: Leveraging Comprehensive Phenotypic and Genotypic Data for Discovery

Por Pendergrass, S.A., Ritchie, M.D.
Publicado no Curr Genet Med Rep (2015)

Kinetic characterization of a cytoplasmic myosin motor domain expressed in Dictyostelium discoideum.

Por Ritchie, M D, Geeves, M A, Woodward, S K, Manstein, D J
Publicado em 1993

Actomyosin kinetics and in vitro motility of wild-type Drosophila actin and the effects of two mutations in the Act88F gene.

Por Anson, M, Drummond, D R, Geeves, M A, Hennessey, E S, Ritchie, M D, Sparrow, J C
Publicado em 1995

Identification of Significant Association and Gene-Gene Interaction of GABA Receptor Subunit Genes in Autism

Por Ma, D. Q., Whitehead, P. L., Menold, M. M., Martin, E. R., Ashley-Koch, A. E., Mei, H., Ritchie, M. D., DeLong, G. R., Abramson, R. K., Wright, H. H., Cuccaro, M. L., Hussman, J. P., Gilbert, J. R., Pericak-Vance, M. A.
Publicado em 2005

The Use of Phenome-Wide Association Studies (PheWAS) for Exploration of Novel Genotype-Phenotype Relationships and Pleiotropy Discovery

Por Pendergrass, S.A., Brown-Gentry, K., Dudek, S.M., Torstenson, E.S., Ambite, J.L., Avery, C.L., Buyske, S., Cai, C., Fesinmeyer, M.D., Haiman, C., Heiss, G., Hindorff, L.A., Hsu, C.-N., Jackson, R.D., Kooperberg, C., Le Marchand, L., Lin, Y., Matise, T.C., Moreland, L., Monroe, K., Reiner, A.P., Wallace, R., Wilkens, L.R., Crawford, D.C., Ritchie, M.D.
Publicado em 2011

Genetic variation in the HLA region is associated with susceptibility to herpes zoster

Por Crosslin, D R, Carrell, D S, Burt, A, Kim, D S, Underwood, J G, Hanna, D S, Comstock, B A, Baldwin, E, de Andrade, M, Kullo, I J, Tromp, G, Kuivaniemi, H, Borthwick, K M, McCarty, C A, Peissig, P L, Doheny, K F, Pugh, E, Kho, A, Pacheco, J, Hayes, M G, Ritchie, M D, Verma, S S, Armstrong, G, Stallings, S, Denny, J C, Carroll, R J, Crawford, D C, Crane, P K, Mukherjee, S, Bottinger, E, Li, R, Keating, B, Mirel, D B, Carlson, C S, Harley, J B, Larson, E B, Jarvik, G P
Publicado no Genes Immun (2015)

A genome-wide association study identifies variants in KCNIP4 associated with ACE inhibitor-induced cough

Por Mosley, J D, Shaffer, C M, Van Driest, S L, Weeke, P E, Wells, Q S, Karnes, J H, Velez Edwards, D R, Wei, W-Q, Teixeira, P L, Bastarache, L, Crawford, D C, Li, R, Manolio, T A, Bottinger, E P, McCarty, C A, Linneman, J G, Brilliant, M H, Pacheco, J A, Thompson, W, Chisholm, R L, Jarvik, G P, Crosslin, D R, Carrell, D S, Baldwin, E, Ralston, J, Larson, E B, Grafton, J, Scrol, A, Jouni, H, Kullo, I J, Tromp, G, Borthwick, K M, Kuivaniemi, H, Carey, D J, Ritchie, M D, Bradford, Y, Verma, S S, Chute, C G, Veluchamy, A, Siddiqui, M K, Palmer, C N A, Doney, A, MahmoudPour, S H, Maitland-van der Zee, A H, Morris, A D, Denny, J C, Roden, D M
Publicado no Pharmacogenomics J (2016)

Genetic and Pharmacologic Inactivation of ANGPTL3 and Cardiovascular Disease

Por Dewey, F.E., Gusarova, V., Dunbar, R.L., O’Dushlaine, C., Schurmann, C., Gottesman, O., McCarthy, S., Van Hout, C.V., Bruse, S., Dansky, H.M., Leader, J.B., Murray, M.F., Ritchie, M.D., Kirchner, H.L., Habegger, L., Lopez, A., Penn, J., Zhao, A., Shao, W., Stahl, N., Murphy, A.J., Hamon, S., Bouzelmat, A., Zhang, R., Shumel, B., Pordy, R., Gipe, D., Herman, G.A., Sheu, W.H.H., Lee, I-T., Liang, K.-W., Guo, X., Rotter, J.I., Chen, Y.-D.I., Kraus, W.E., Shah, S.H., Damrauer, S., Small, A., Rader, D.J., Wulff, A.B., Nordestgaard, B.G., Tybjærg-Hansen, A., van den Hoek, A.M., Princen, H.M.G., Ledbetter, D.H., Carey, D.J., Overton, J.D., Reid, J.G., Sasiela, W.J., Banerjee, P., Shuldiner, A.R., Borecki, I.B., Teslovich, T.M., Yancopoulos, G.D., Mellis, S.J., Gromada, J., Baras, A.
Publicado no N Engl J Med (2017)