Intracerebral Administration of a Ligand-ASO Conjugate Selectively Reduces α-Synuclein Accumulation in Monoamine Neurons of Double Mutant Human A30P*A53T*α-Synuclein Transgenic Mic...

per Pavia-Collado, Rubén, Cóppola-Segovia, Valentín, Miquel-Rio, Lluís, Alarcón-Aris, Diana, Rodríguez-Aller, Raquel, Torres-López, María, Paz, Verónica, Ruiz-Bronchal, Esther, Campa, Leticia, Artigas, Francesc, Montefeltro, Andrés, Revilla, Raquel, Bortolozzi, Analia
Publicat a Int J Mol Sci (2021)

Selective α-Synuclein Knockdown in Monoamine Neurons by Intranasal Oligonucleotide Delivery: Potential Therapy for Parkinson’s Disease

per Alarcón-Arís, Diana, Recasens, Ariadna, Galofré, Mireia, Carballo-Carbajal, Iria, Zacchi, Nicolás, Ruiz-Bronchal, Esther, Pavia-Collado, Rubén, Chica, Rosario, Ferrés-Coy, Albert, Santos, Marina, Revilla, Raquel, Montefeltro, Andrés, Fariñas, Isabel, Artigas, Francesc, Vila, Miquel, Bortolozzi, Analia
Publicat a Mol Ther (2018)

Anti-α-synuclein ASO delivered to monoamine neurons prevents α-synuclein accumulation in a Parkinson's disease-like mouse model and in monkeys

per Alarcón-Arís, Diana, Pavia-Collado, Rubén, Miquel-Rio, Lluis, Coppola-Segovia, Valentín, Ferrés-Coy, Albert, Ruiz-Bronchal, Esther, Galofré, Mireia, Paz, Verónica, Campa, Leticia, Revilla, Raquel, Montefeltro, Andrés, Kordower, Jeffrey H., Vila, Miquel, Artigas, Francesc, Bortolozzi, Analia
Publicat a EBioMedicine (2020)