Snapshots of ligand entry, malleable binding and induced helical movement in P-glycoprotein

door Szewczyk, Paul, Tao, Houchao, McGrath, Aaron P., Villaluz, Mark, Rees, Steven D., Lee, Sung Chang, Doshi, Rupak, Urbatsch, Ina L., Zhang, Qinghai, Chang, Geoffrey
Gepubliceerd in Acta Crystallogr D Biol Crystallogr (2015)

Structural basis for GPCR-independent activation of heterotrimeric Gi proteins

door Kalogriopoulos, Nicholas A., Rees, Steven D., Ngo, Tony, Kopcho, Noah J., Ilatovskiy, Andrey V., Sun, Nina, Komives, Elizabeth A., Chang, Geoffrey, Ghosh, Pradipta, Kufareva, Irina
Gepubliceerd in Proc Natl Acad Sci U S A (2019)

Global marine pollutants inhibit P-glycoprotein: Environmental levels, inhibitory effects, and cocrystal structure

door Nicklisch, Sascha C. T., Rees, Steven D., McGrath, Aaron P., Gökirmak, Tufan, Bonito, Lindsay T., Vermeer, Lydia M., Cregger, Cristina, Loewen, Greg, Sandin, Stuart, Chang, Geoffrey, Hamdoun, Amro
Gepubliceerd in Sci Adv (2016)

Gut bacteria responding to dietary change encode sialidases that exhibit preference for red meat-associated carbohydrates

door Zaramela, Livia S., Martino, Cameron, Alisson-Silva, Frederico, Rees, Steven D., Diaz, Sandra L., Chuzel, Léa, Ganatra, Mehul B., Taron, Christopher H., Secrest, Patrick, Zuñiga, Cristal, Huang, Jianbo, Siegel, Dionicio, Chang, Geoffrey, Varki, Ajit, Zengler, Karsten
Gepubliceerd in Nat Microbiol (2019)

Cryo-EM structure of OSCA1.2 from Oryza sativa elucidates the mechanical basis of potential membrane hyperosmolality gating

door Maity, Koustav, Heumann, John M., McGrath, Aaron P., Kopcho, Noah J., Hsu, Po-Kai, Lee, Chang-Wook, Mapes, James H., Garza, Denisse, Krishnan, Srinivasan, Morgan, Garry P., Hendargo, Kevin J., Klose, Thomas, Rees, Steven D., Medrano-Soto, Arturo, Saier, Milton H., Piñeros, Miguel, Komives, Elizabeth A., Schroeder, Julian I., Chang, Geoffrey, Stowell, Michael H. B.
Gepubliceerd in Proc Natl Acad Sci U S A (2019)