Snapshots of ligand entry, malleable binding and induced helical movement in P-glycoprotein

Por Szewczyk, Paul, Tao, Houchao, McGrath, Aaron P., Villaluz, Mark, Rees, Steven D., Lee, Sung Chang, Doshi, Rupak, Urbatsch, Ina L., Zhang, Qinghai, Chang, Geoffrey
Publicado no Acta Crystallogr D Biol Crystallogr (2015)

Structural basis for GPCR-independent activation of heterotrimeric Gi proteins

Por Kalogriopoulos, Nicholas A., Rees, Steven D., Ngo, Tony, Kopcho, Noah J., Ilatovskiy, Andrey V., Sun, Nina, Komives, Elizabeth A., Chang, Geoffrey, Ghosh, Pradipta, Kufareva, Irina
Publicado no Proc Natl Acad Sci U S A (2019)

Global marine pollutants inhibit P-glycoprotein: Environmental levels, inhibitory effects, and cocrystal structure

Por Nicklisch, Sascha C. T., Rees, Steven D., McGrath, Aaron P., Gökirmak, Tufan, Bonito, Lindsay T., Vermeer, Lydia M., Cregger, Cristina, Loewen, Greg, Sandin, Stuart, Chang, Geoffrey, Hamdoun, Amro
Publicado no Sci Adv (2016)

Gut bacteria responding to dietary change encode sialidases that exhibit preference for red meat-associated carbohydrates

Por Zaramela, Livia S., Martino, Cameron, Alisson-Silva, Frederico, Rees, Steven D., Diaz, Sandra L., Chuzel, Léa, Ganatra, Mehul B., Taron, Christopher H., Secrest, Patrick, Zuñiga, Cristal, Huang, Jianbo, Siegel, Dionicio, Chang, Geoffrey, Varki, Ajit, Zengler, Karsten
Publicado no Nat Microbiol (2019)

Cryo-EM structure of OSCA1.2 from Oryza sativa elucidates the mechanical basis of potential membrane hyperosmolality gating

Por Maity, Koustav, Heumann, John M., McGrath, Aaron P., Kopcho, Noah J., Hsu, Po-Kai, Lee, Chang-Wook, Mapes, James H., Garza, Denisse, Krishnan, Srinivasan, Morgan, Garry P., Hendargo, Kevin J., Klose, Thomas, Rees, Steven D., Medrano-Soto, Arturo, Saier, Milton H., Piñeros, Miguel, Komives, Elizabeth A., Schroeder, Julian I., Chang, Geoffrey, Stowell, Michael H. B.
Publicado no Proc Natl Acad Sci U S A (2019)