Duchenne muscular dystrophy mice and men: Can understanding a genetic cardiomyopathy inform treatment of other myocardial diseases?

Por Rafael-Fortney, Jill A., Chadwick, Jessica A., Raman, Subha V.
Publicado no Circ Res (2016)

Cardiac Involvement in Patients with Muscular Dystrophies: Magnetic Resonance Imaging Phenotype and Genotypic Considerations

Por Verhaert, David, Richards, Kathryn, Rafael-Fortney, Jill A., Raman, Subha V.
Publicado em 2011

Lengthening-contractions in isolated myocardium impact force development and worsen cardiac contractile function in the mdx mouse model of muscular dystrophy

Por Xu, Ying, Delfín, Dawn A., Rafael-Fortney, Jill A., Janssen, Paul M. L.
Publicado em 2011

Renin-angiotensin-aldosterone system inhibitors improve membrane stability and change gene-expression profiles in dystrophic skeletal muscles

Por Chadwick, Jessica A., Bhattacharya, Sayak, Lowe, Jeovanna, Weisleder, Noah, Rafael-Fortney, Jill A.
Publicado no Am J Physiol Cell Physiol (2017)

GLUTAMATE RECEPTORS LOCALIZE POSTSYNAPTICALLY AT NEUROMUSCULAR JUNCTIONS IN MICE

Por MAYS, TESSILY A., SANFORD, JAMIE L., HANADA, TOSHIHIKO, CHISHTI, ATHAR H., RAFAEL-FORTNEY, JILL A.
Publicado em 2009

Cytoplasmic γ-actin contributes to a compensatory remodeling response in dystrophin-deficient muscle

Por Hanft, Laurin M., Rybakova, Inna N., Patel, Jitandrakumar R., Rafael-Fortney, Jill A., Ervasti, James M.
Publicado em 2006

Myocardial Contractile Dysfunction Is Present without Histopathology in a Mouse Model of Limb-Girdle Muscular Dystrophy-2F and Is Prevented after Claudin-5 Virotherapy

Por Milani-Nejad, Nima, Schultz, Eric J., Slabaugh, Jessica L., Janssen, Paul M. L., Rafael-Fortney, Jill A.
Publicado no Front Physiol (2016)

Improvement of cardiac contractile function by peptide-based inhibition of NF-κB in the utrophin/dystrophin-deficient murine model of muscular dystrophy

Por Delfín, Dawn A, Xu, Ying, Peterson, Jennifer M, Guttridge, Denis C, Rafael-Fortney, Jill A, Janssen, Paul ML
Publicado em 2011

Gene expression effects of glucocorticoid and mineralocorticoid receptor agonists and antagonists on normal human skeletal muscle

Por Chadwick, Jessica A., Hauck, J. Spencer, Gomez-Sanchez, Celso E., Gomez-Sanchez, Elise P., Rafael-Fortney, Jill A.
Publicado no Physiol Genomics (2017)

Muscle Damage, Metabolism, & Oxidative Stress in mdx Mice: Impact of Aerobic Running

Por Schill, Kevin E., Altenberger, Alex R., Lowe, Jeovanna, Periasamy, Muthu, Villamena, Frederick A., Rafael-Fortney, Jill A., Devor, Steven T.
Publicado no Muscle Nerve (2016)

Haploinsufficiency of Utrophin Gene Worsens Skeletal Muscle Inflammation and Fibrosis in mdx Mice

Por Zhou, Lan, Rafael-Fortney, Jill A., Huang, Ping, Zhao, Xinyu S., Cheng, Georgiana, Zhou, Xiaohua, Kaminski, Henry J., Liu, Liping, Ransohoff, Richard M.
Publicado em 2007

Cardiomyopathy in the dystrophin/utrophin-deficient mouse model of severe muscular dystrophy is characterized by dysregulation of matrix metalloproteinases

Por Delfín, Dawn A., Zang, Kara E., Schill, Kevin E., Patel, Nikita T., Janssen, Paul M.L., Raman, Subha V., Rafael-Fortney, Jill A.
Publicado em 2012

The force-temperature relationship in healthy and dystrophic mouse diaphragm; implications for translational study design

Por Murray, Jason D., Canan, Benjamin D., Martin, Christopher D., Stangland, Jenna E., Rastogi, Neha, Rafael-Fortney, Jill A., Janssen, Paul M. L.
Publicado em 2012

Standard Operating Procedures (SOPs) for Evaluating the Heart in Preclinical Studies of Duchenne Muscular Dystrophy

Por Duan, Dongsheng, Rafael-Fortney, Jill A., Blain, Alison, Kass, David A., McNally, Elizabeth M., Metzger, Joseph M., Spurney, Christopher F., Kinnett, Kathi
Publicado no J Cardiovasc Transl Res (2015)

Prednisolone Attenuates Improvement of Cardiac and Skeletal Contractile Function and Histopathology by Lisinopril and Spironolactone in the mdx Mouse Model of Duchenne Muscular Dys...

Por Janssen, Paul M. L., Murray, Jason D., Schill, Kevin E., Rastogi, Neha, Schultz, Eric J., Tran, Tam, Raman, Subha V., Rafael-Fortney, Jill A.
Publicado em 2014

Mineralocorticoid receptors are present in skeletal muscle and represent a potential therapeutic target

Por Chadwick, Jessica A., Hauck, J. Spencer, Lowe, Jeovanna, Shaw, Jeremiah J., Guttridge, Denis C., Gomez-Sanchez, Celso E., Gomez-Sanchez, Elise P., Rafael-Fortney, Jill A.
Publicado no FASEB J (2015)

Sustaining Cardiac Claudin-5 Levels Prevents Functional Hallmarks of Cardiomyopathy in a Muscular Dystrophy Mouse Model

Por Delfín, Dawn A, Xu, Ying, Schill, Kevin E, Mays, Tessily A, Canan, Benjamin D, Zang, Kara E, Barnum, Jamie A, Janssen, Paul ML, Rafael-Fortney, Jill A
Publicado em 2012

The Angiotensin Converting Enzyme Inhibitor Lisinopril Improves Muscle Histopathology but not Contractile Function in a Mouse Model of Duchenne Muscular Dystrophy

Por Lowe, Jeovanna, Wodarcyk, Andrew J., Floyd, Kyle T., Rastogi, Neha, Schultz, Eric J., Swager, Sarah A., Chadwick, Jessica A., Tran, Tam, Raman, Subha V., Janssen, Paul M.L., Rafael-Fortney, Jill A.
Publicado no J Neuromuscul Dis (2015)

Impairment of Diastolic Function by Lack of Frequency-Dependent Myofilament Desensitization in Rabbit Right Ventricular Hypertrophy

Por Varian, Kenneth D., Kijtawornrat, Anusak, Gupta, Subash C., Torres, Carlos A.A., Monasky, Michelle M., Hiranandani, Nitisha, Delfin, Dawn A., Rafael-Fortney, Jill A., Periasamy, Muthu, Hamlin, Robert L., Janssen, Paul M.L.
Publicado em 2009

Claudin-5 levels are reduced from multiple cell types in human failing hearts and are associated with mislocalization of ephrin-B1

Por Swager, Sarah A., Delfín, Dawn A., Rastogi, Neha, Wang, Honglan, Canan, Benjamin D., Fedorov, Vadim V., Mohler, Peter J., Kilic, Ahmet, Higgins, Robert S.D., Ziolo, Mark T., Janssen, Paul M.L., Rafael-Fortney, Jill A.
Publicado no Cardiovasc Pathol (2014)