Reactive Astrocytes Derived From Human Induced Pluripotent Stem Cells Suppress Oligodendrocyte Precursor Cell Differentiation

by Matthew D. Smith, Xitiz Chamling, Alexander J. Gill, Hector Martinez, Weifeng Li, Weifeng Li, Kathryn C. Fitzgerald, Elias S. Sotirchos, Dorota Moroziewicz, Lauren Bauer, Daniel Paull, Marjan Gharagozloo, Pavan Bhargava, Donald J. Zack, Donald J. Zack, Donald J. Zack, Donald J. Zack, Valentina Fossati, Peter A. Calabresi, Peter A. Calabresi, Peter A. Calabresi
Published 2022-05-01

A comparison of supervised machine learning algorithms and feature vectors for MS lesion segmentation using multimodal structural MRI.

by Elizabeth M Sweeney, Joshua T Vogelstein, Jennifer L Cuzzocreo, Peter A Calabresi, Daniel S Reich, Ciprian M Crainiceanu, Russell T Shinohara
Published 2014-01-01

Blockade of Kv1.3 potassium channels inhibits differentiation and granzyme B secretion of human CD8+ T effector memory lymphocytes.

by Lina Hu, Tongguang Wang, Anne R Gocke, Avindra Nath, Hao Zhang, Joseph B Margolick, Katharine A Whartenby, Peter A Calabresi
Published 2013-01-01

Proteomic Alterations and Novel Markers of Neurotoxic Reactive Astrocytes in Human Induced Pluripotent Stem Cell Models

by David Labib, Zhen Wang, Zhen Wang, Priya Prakash, Matthew Zimmer, Matthew D. Smith, Paul W. Frazel, Lilianne Barbar, Maria L. Sapar, Peter A. Calabresi, Peter A. Calabresi, Junmin Peng, Junmin Peng, Junmin Peng, Shane A. Liddelow, Shane A. Liddelow, Shane A. Liddelow, Shane A. Liddelow, Valentina Fossati
Published 2022-05-01

Granzyme B-induced neurotoxicity is mediated via activation of PAR-1 receptor and Kv1.3 channel.

by Tongguang Wang, Myoung-Hwa Lee, Elliot Choi, Carlos A Pardo-Villamizar, Sung Bin Lee, In Hong Yang, Peter A Calabresi, Avindra Nath
Published 2012-01-01

Targeting Repulsive Guidance Molecule A to Promote Regeneration and Neuroprotection in Multiple Sclerosis

by Elena Demicheva, Yi-Fang Cui, Philip Bardwell, Stefan Barghorn, Martina Kron, Axel H. Meyer, Martin Schmidt, Björn Gerlach, Mary Leddy, Eve Barlow, Elizabeth O’Connor, Chee-Ho Choi, Lili Huang, Geertruida M. Veldman, Horea Rus, Alireza P. Shabanzadeh, Nardos G. Tassew, Philippe P. Monnier, Thomas Müller, Peter A. Calabresi, Hans Schoemaker, Bernhard K. Mueller
Published 2015-03-01