NOTCH1 represses MCL-1 levels in GSI-resistant T-ALL, making them susceptible to ABT-263

af Dastur, Anahita, Choi, AHyun, Costa, Carlotta, Yin, Xunqin, Williams, August, McClanaghan, Joseph, Greenberg, Max, Roderick, Justine, Patel, Neha U., Boisvert, Jessica, McDermott, Ultan, Garnett, Mathew J., Almenara, Jorge, Grant, Steven, Rizzo, Kathryn, Engelman, Jeffrey A., Kelliher, Michelle, Faber, Anthony C., Benes, Cyril H.
Udgivet i Clin Cancer Res (2018)

Assessment of ABT-263 activity across a cancer cell line collection leads to a potent combination therapy for small-cell lung cancer

af Faber, Anthony C., Farago, Anna F., Costa, Carlotta, Dastur, Anahita, Gomez-Caraballo, Maria, Robbins, Rebecca, Wagner, Bethany L., Rideout, William M., Jakubik, Charles T., Ham, Jungoh, Edelman, Elena J., Ebi, Hiromichi, Yeo, Alan T., Hata, Aaron N., Song, Youngchul, Patel, Neha U., March, Ryan J., Tam, Ah Ting, Milano, Randy J., Boisvert, Jessica L., Hicks, Mark A., Elmiligy, Sarah, Malstrom, Scott E., Rivera, Miguel N., Harada, Hisashi, Windle, Brad E., Ramaswamy, Sridhar, Benes, Cyril H., Jacks, Tyler, Engelman, Jeffrey A.
Udgivet i Proc Natl Acad Sci U S A (2015)

Epithelial-to-mesenchymal transition antagonizes response to targeted therapies in lung cancer by suppressing BIM

af Song, Kyung-A, Niederst, Matthew J., Lochmann, Timothy L., Hata, Aaron N., Kitai, Hidenori, Ham, Jungoh, Floros, Konstantinos V., Hicks, Mark A., Hu, Haichuan, Mulvey, Hillary E., Drier, Yotam, Heisey, Daniel A.R., Hughes, Mark T., Patel, Neha U., Lockerman, Elizabeth L., Garcia, Angel, Gillepsie, Shawn, Archibald, Hannah L., Gomez-Caraballo, Maria, Nulton, Tara J., Windle, Brad E., Piotrowska, Zofia, Sahingur, Sinem E., Taylor, Shirley M., Dozmorov, Mikhail, Sequist, Lecia V., Bernstein, Bradley, Ebi, Hiromichi, Engelman, Jeffrey A., Faber, Anthony C.
Udgivet i Clin Cancer Res (2017)

Exploitation of the Apoptosis-Primed State of MYCN-Amplified Neuroblastoma to Develop a Potent and Specific Targeted Therapy Combination

af Ham, Jungoh, Costa, Carlotta, Sano, Renata, Lochmann, Timothy L., Sennott, Erin M., Patel, Neha U., Dastur, Anahita, Gomez-Caraballo, Maria, Krytska, Kateryna, Hata, Aaron N., Floros, Konstantinos V., Hughes, Mark T., Jakubik, Charles T., Heisey, Daniel A.R., Ferrell, Justin T., Bristol, Molly L., March, Ryan J., Yates, Craig, Hicks, Mark A., Nakajima, Wataru, Gowda, Madhu, Windle, Brad E., Dozmorov, Mikhail G., Garnett, Mathew J., McDermott, Ultan, Harada, Hisashi, Taylor, Shirley M., Morgan, Iain M., Benes, Cyril H., Engelman, Jeffrey A., Mossé, Yael P., Faber, Anthony C.
Udgivet i Cancer Cell (2016)