Wild-type huntingtin regulates human macrophage function

door O’Regan, Grace C., Farag, Sahar H., Ostroff, Gary R., Tabrizi, Sarah J., Andre, Ralph
Gepubliceerd in Sci Rep (2020)

Human Huntington’s disease pluripotent stem cell-derived microglia develop normally but are abnormally hyper-reactive and release elevated levels of reactive oxygen species

door O’Regan, Grace C., Farag, Sahar H., Casey, Caroline S., Wood-Kaczmar, Alison, Pocock, Jennifer M., Tabrizi, Sarah J., Andre, Ralph
Gepubliceerd in J Neuroinflammation (2021)