Obesity and Cancer Metabolism: A Perspective on Interacting Tumor–Intrinsic and Extrinsic Factors

Por Doerstling, Steven S., O’Flanagan, Ciara H., Hursting, Stephen D.
Publicado no Front Oncol (2017)

PINK1, cancer and neurodegeneration

Por O'Flanagan, Ciara H., Morais, Vanessa A., O'Neill, Cora
Publicado no Oncoscience (2016)

A weighty problem: metabolic perturbations and the obesity-cancer link

Por O’Flanagan, Ciara H., Bowers, Laura W., Hursting, Stephen D.
Publicado no Horm Mol Biol Clin Investig (2015)

When less may be more: calorie restriction and response to cancer therapy

Por O’Flanagan, Ciara H., Smith, Laura A., McDonell, Shannon B., Hursting, Stephen D.
Publicado no BMC Med (2017)

The Role of the Insulin/IGF System in Cancer: Lessons Learned from Clinical Trials and the Energy Balance-Cancer Link

Por Bowers, Laura W., Rossi, Emily L., O’Flanagan, Ciara H., deGraffenried, Linda A., Hursting, Stephen D.
Publicado no Front Endocrinol (Lausanne) (2015)

IGF-1R inhibition sensitizes breast cancer cells to ATM-related kinase (ATR) inhibitor and cisplatin

Por O'Flanagan, Ciara H., O'shea, Sandra, Lyons, Amy, Fogarty, Fionola M., McCabe, Nuala, Kennedy, Richard D., O'Connor, Rosemary
Publicado no Oncotarget (2016)

Insulin-like growth factor 1 signaling is essential for mitochondrial biogenesis and mitophagy in cancer cells

Por Lyons, Amy, Coleman, Michael, Riis, Sarah, Favre, Cedric, O'Flanagan, Ciara H., Zhdanov, Alexander V., Papkovsky, Dmitri B., Hursting, Stephen D., O'Connor, Rosemary
Publicado no J Biol Chem (2017)

Metabolic reprogramming underlies metastatic potential in an obesity-responsive murine model of metastatic triple negative breast cancer

Por O’Flanagan, Ciara H., Rossi, Emily L., McDonell, Shannon B., Chen, Xuewen, Tsai, Yi-Hsuan, Parker, Joel S., Usary, Jerry, Perou, Charles M., Hursting, Stephen D.
Publicado no NPJ Breast Cancer (2017)

Starving cancer from the outside and inside: separate and combined effects of calorie restriction and autophagy inhibition on Ras-driven tumors

Por Lashinger, Laura M., O’Flanagan, Ciara H., Dunlap, Sarah M., Rasmussen, Audrey J., Sweeney, Shannon, Guo, Jessie Yangxiang, Lodi, Alessia, Tiziani, Stefano, White, Eileen, Hursting, Stephen D.
Publicado no Cancer Metab (2016)