CD8(+) T cells in cutaneous leishmaniasis: The good, the bad and the ugly

door Novais, Fernanda O., Scott, Phillip
Gepubliceerd in Semin Immunopathol (2015)

Granzyme B inhibition by tofacitinib blocks pathology induced by CD8 T cells in cutaneous leishmaniasis

door Novais, Fernanda O., Nguyen, Ba T., Scott, Phillip
Gepubliceerd in J Invest Dermatol (2020)

Host-Directed Therapies for Cutaneous Leishmaniasis

door Novais, Fernanda O., Amorim, Camila Farias, Scott, Phillip
Gepubliceerd in Front Immunol (2021)

Lymphocytic choriomeningitis virus expands a population of NKG2D(+)CD8(+) T cells that exacerbate disease in mice co-infected with Leishmania major

door Crosby, Erika J., Clark, Megan, Novais, Fernanda O., Wherry, E. John, Scott, Phillip
Gepubliceerd in J Immunol (2015)

CD8+ T cells lack local signals to produce IFN-γ in the skin during leishmania infection

door Novais, Fernanda O., Wong, Andrea C., Villareal§, Daniel O., Beiting, Daniel P., Scott*, Phillip
Gepubliceerd in J Immunol (2018)

Genomic profiling of human Leishmania braziliensis lesions identifies transcriptional modules associated with cutaneous immunopathology

door Novais, Fernanda O., Carvalho, Lucas P., Passos, Sara, Roos, David S., Carvalho, Edgar M., Scott, Phillip, Beiting, Daniel P.
Gepubliceerd in J Invest Dermatol (2014)

Toward a Novel Experimental Model of Infection To Study American Cutaneous Leishmaniasis Caused by Leishmania braziliensis

door de Moura, Tatiana R., Novais, Fernanda O., Oliveira, Fabiano, Clarêncio, Jorge, Noronha, Almério, Barral, Aldina, Brodskyn, Claudia, de Oliveira, Camila I.
Gepubliceerd in 2005

Human Classical Monocytes Control the Intracellular Stage of Leishmania braziliensis by Reactive Oxygen Species

door Novais, Fernanda O., Nguyen, Ba T., Beiting, Daniel P., Carvalho, Lucas P., Glennie, Nelson D., Passos, Sara, Carvalho, Edgar M., Scott, Phillip
Gepubliceerd in 2014

Variable gene expression and parasite load predict treatment outcome in cutaneous leishmaniasis

door Amorim, Camila Farias, Novais, Fernanda O., Nguyen, Ba T., Misic, Ana M., Carvalho, Lucas P., Carvalho, Edgar M., Beiting, Daniel P., Scott, Phillip
Gepubliceerd in Sci Transl Med (2019)

CD8(+) T cell cytotoxicity mediates pathology in the skin by inflammasome activation and IL-1β production

door Novais, Fernanda O., Carvalho, Augusto M., Clark, Megan L., Carvalho, Lucas P., Beiting, Daniel P., Brodsky, Igor E., Carvalho, Edgar M., Scott, Phillip
Gepubliceerd in PLoS Pathog (2017)

Glyburide, a NLRP3 Inhibitor, Decreases Inflammatory Response and Is a Candidate to Reduce Pathology in Leishmania braziliensis Infection

door Carvalho, Augusto M., Novais, Fernanda, O., Paixão, Camilla S., de Oliveira, Camila I., Machado, Paulo Roberto Lima, Carvalho, Lucas P., Scott, Phillip, Carvalho, Edgar M.
Gepubliceerd in J Invest Dermatol (2019)

Matrix Metalloproteinase 9 Production by Monocytes is Enhanced by TNF and Participates in the Pathology of Human Cutaneous Leishmaniasis

door Campos, Taís M., Passos, Sara T., Novais, Fernanda O., Beiting, Daniel P., Costa, Rúbia S., Queiroz, Adriano, Mosser, David, Scott, Phillip, Carvalho, Edgar M., Carvalho, Lucas P.
Gepubliceerd in PLoS Negl Trop Dis (2014)

Intermediate Monocytes Contribute to Pathologic Immune Response in Leishmania braziliensis Infections

door Passos, Sara, Carvalho, Lucas P., Costa, Rúbia S., Campos, Taís M., Novais, Fernanda O., Magalhães, Andréa, Machado, Paulo R. L., Beiting, Daniel, Mosser, David, Carvalho, Edgar M., Scott, Phillip
Gepubliceerd in J Infect Dis (2015)

Cytotoxic T Cells Mediate Pathology and Metastasis in Cutaneous Leishmaniasis

door Novais, Fernanda O., Carvalho, Lucas P., Graff, Joel W., Beiting, Daniel P., Ruthel, Gordon, Roos, David S., Betts, Michael R., Goldschmidt, Michael H., Wilson, Mary E., de Oliveira, Camila I., Scott, Phillip
Gepubliceerd in 2013

Immunity to Lutzomyia intermedia Saliva Modulates the Inflammatory Environment Induced by Leishmania braziliensis

door de Moura, Tatiana R., Oliveira, Fabiano, Rodrigues, Gabriele C., Carneiro, Marcia W., Fukutani, Kiyoshi F., Novais, Fernanda O., Miranda, José Carlos, Barral-Netto, Manoel, Brodskyn, Claudia, Barral, Aldina, de Oliveira, Camila I.
Gepubliceerd in 2010

Granzyme B Produced by Natural Killer Cells Enhances Inflammatory Response and Contributes to the Immunopathology of Cutaneous Leishmaniasis

door Campos, Taís M, Novais, Fernanda O, Saldanha, Maíra, Costa, Rúbia, Lordelo, Morgana, Celestino, Daniela, Sampaio, Camilla, Tavares, Natália, Arruda, Sérgio, Machado, Paulo, Brodskyn, Cláudia, Scott, Phillip, Carvalho, Edgar M, Carvalho, Lucas P
Gepubliceerd in J Infect Dis (2020)

Enhanced Leishmania braziliensis Infection Following Pre-Exposure to Sandfly Saliva

door de Moura, Tatiana R., Oliveira, Fabiano, Novais, Fernanda O., Miranda, José Carlos, Clarêncio, Jorge, Follador, Ivonise, Carvalho, Edgar M., Valenzuela, Jesus G., Barral-Netto, Manoel, Barral, Aldina, Brodskyn, Cláudia, de Oliveira, Camila I.
Gepubliceerd in 2007

Meta-transcriptome Profiling of the Human-Leishmania braziliensis Cutaneous Lesion

door Christensen, Stephen M., Dillon, Laura A. L., Carvalho, Lucas P., Passos, Sara, Novais, Fernanda O., Hughitt, V. Keith, Beiting, Daniel P., Carvalho, Edgar M., Scott, Phillip, El-Sayed, Najib M., Mosser, David M.
Gepubliceerd in PLoS Negl Trop Dis (2016)

Correction: Meta-transcriptome Profiling of the Human-Leishmania braziliensis Cutaneous Lesion

door Christensen, Stephen M., Dillon, Laura A. L., Carvalho, Lucas P., Passos, Sara, Novais, Fernanda O., Hughitt, V. Keith, Beiting, Daniel P., Carvalho, Edgar M., Scott, Phillip, El-Sayed, Najib M., Mosser, David M.
Gepubliceerd in PLoS Negl Trop Dis (2017)

Cutaneous leishmaniasis induces a transmissible dysbiotic skin microbiota that promotes skin inflammation

door Gimblet, Ciara, Meisel, Jacquelyn S., Loesche, Michael A., Cole, Stephen D., Horwinski, Joseph, Novais, Fernanda O., Misic, Ana M., Bradley, Charles W., Beiting, Daniel P., Rankin, Shelley C., Carvalho, Lucas P., Carvalho, Edgar M., Phillip, Scott, Grice, Elizabeth A.
Gepubliceerd in Cell Host Microbe (2017)