CD8(+) T cells in cutaneous leishmaniasis: The good, the bad and the ugly

Por Novais, Fernanda O., Scott, Phillip
Publicado no Semin Immunopathol (2015)

Granzyme B inhibition by tofacitinib blocks pathology induced by CD8 T cells in cutaneous leishmaniasis

Por Novais, Fernanda O., Nguyen, Ba T., Scott, Phillip
Publicado no J Invest Dermatol (2020)

Host-Directed Therapies for Cutaneous Leishmaniasis

Por Novais, Fernanda O., Amorim, Camila Farias, Scott, Phillip
Publicado no Front Immunol (2021)

Lymphocytic choriomeningitis virus expands a population of NKG2D(+)CD8(+) T cells that exacerbate disease in mice co-infected with Leishmania major

Por Crosby, Erika J., Clark, Megan, Novais, Fernanda O., Wherry, E. John, Scott, Phillip
Publicado no J Immunol (2015)

CD8+ T cells lack local signals to produce IFN-γ in the skin during leishmania infection

Por Novais, Fernanda O., Wong, Andrea C., Villareal§, Daniel O., Beiting, Daniel P., Scott*, Phillip
Publicado no J Immunol (2018)

Genomic profiling of human Leishmania braziliensis lesions identifies transcriptional modules associated with cutaneous immunopathology

Por Novais, Fernanda O., Carvalho, Lucas P., Passos, Sara, Roos, David S., Carvalho, Edgar M., Scott, Phillip, Beiting, Daniel P.
Publicado no J Invest Dermatol (2014)

Toward a Novel Experimental Model of Infection To Study American Cutaneous Leishmaniasis Caused by Leishmania braziliensis

Por de Moura, Tatiana R., Novais, Fernanda O., Oliveira, Fabiano, Clarêncio, Jorge, Noronha, Almério, Barral, Aldina, Brodskyn, Claudia, de Oliveira, Camila I.
Publicado em 2005

Human Classical Monocytes Control the Intracellular Stage of Leishmania braziliensis by Reactive Oxygen Species

Por Novais, Fernanda O., Nguyen, Ba T., Beiting, Daniel P., Carvalho, Lucas P., Glennie, Nelson D., Passos, Sara, Carvalho, Edgar M., Scott, Phillip
Publicado em 2014

Variable gene expression and parasite load predict treatment outcome in cutaneous leishmaniasis

Por Amorim, Camila Farias, Novais, Fernanda O., Nguyen, Ba T., Misic, Ana M., Carvalho, Lucas P., Carvalho, Edgar M., Beiting, Daniel P., Scott, Phillip
Publicado no Sci Transl Med (2019)

CD8(+) T cell cytotoxicity mediates pathology in the skin by inflammasome activation and IL-1β production

Por Novais, Fernanda O., Carvalho, Augusto M., Clark, Megan L., Carvalho, Lucas P., Beiting, Daniel P., Brodsky, Igor E., Carvalho, Edgar M., Scott, Phillip
Publicado no PLoS Pathog (2017)

Glyburide, a NLRP3 Inhibitor, Decreases Inflammatory Response and Is a Candidate to Reduce Pathology in Leishmania braziliensis Infection

Por Carvalho, Augusto M., Novais, Fernanda, O., Paixão, Camilla S., de Oliveira, Camila I., Machado, Paulo Roberto Lima, Carvalho, Lucas P., Scott, Phillip, Carvalho, Edgar M.
Publicado no J Invest Dermatol (2019)

Matrix Metalloproteinase 9 Production by Monocytes is Enhanced by TNF and Participates in the Pathology of Human Cutaneous Leishmaniasis

Por Campos, Taís M., Passos, Sara T., Novais, Fernanda O., Beiting, Daniel P., Costa, Rúbia S., Queiroz, Adriano, Mosser, David, Scott, Phillip, Carvalho, Edgar M., Carvalho, Lucas P.
Publicado no PLoS Negl Trop Dis (2014)

Intermediate Monocytes Contribute to Pathologic Immune Response in Leishmania braziliensis Infections

Por Passos, Sara, Carvalho, Lucas P., Costa, Rúbia S., Campos, Taís M., Novais, Fernanda O., Magalhães, Andréa, Machado, Paulo R. L., Beiting, Daniel, Mosser, David, Carvalho, Edgar M., Scott, Phillip
Publicado no J Infect Dis (2015)

Cytotoxic T Cells Mediate Pathology and Metastasis in Cutaneous Leishmaniasis

Por Novais, Fernanda O., Carvalho, Lucas P., Graff, Joel W., Beiting, Daniel P., Ruthel, Gordon, Roos, David S., Betts, Michael R., Goldschmidt, Michael H., Wilson, Mary E., de Oliveira, Camila I., Scott, Phillip
Publicado em 2013

Immunity to Lutzomyia intermedia Saliva Modulates the Inflammatory Environment Induced by Leishmania braziliensis

Por de Moura, Tatiana R., Oliveira, Fabiano, Rodrigues, Gabriele C., Carneiro, Marcia W., Fukutani, Kiyoshi F., Novais, Fernanda O., Miranda, José Carlos, Barral-Netto, Manoel, Brodskyn, Claudia, Barral, Aldina, de Oliveira, Camila I.
Publicado em 2010

Granzyme B Produced by Natural Killer Cells Enhances Inflammatory Response and Contributes to the Immunopathology of Cutaneous Leishmaniasis

Por Campos, Taís M, Novais, Fernanda O, Saldanha, Maíra, Costa, Rúbia, Lordelo, Morgana, Celestino, Daniela, Sampaio, Camilla, Tavares, Natália, Arruda, Sérgio, Machado, Paulo, Brodskyn, Cláudia, Scott, Phillip, Carvalho, Edgar M, Carvalho, Lucas P
Publicado no J Infect Dis (2020)

Enhanced Leishmania braziliensis Infection Following Pre-Exposure to Sandfly Saliva

Por de Moura, Tatiana R., Oliveira, Fabiano, Novais, Fernanda O., Miranda, José Carlos, Clarêncio, Jorge, Follador, Ivonise, Carvalho, Edgar M., Valenzuela, Jesus G., Barral-Netto, Manoel, Barral, Aldina, Brodskyn, Cláudia, de Oliveira, Camila I.
Publicado em 2007

Meta-transcriptome Profiling of the Human-Leishmania braziliensis Cutaneous Lesion

Por Christensen, Stephen M., Dillon, Laura A. L., Carvalho, Lucas P., Passos, Sara, Novais, Fernanda O., Hughitt, V. Keith, Beiting, Daniel P., Carvalho, Edgar M., Scott, Phillip, El-Sayed, Najib M., Mosser, David M.
Publicado no PLoS Negl Trop Dis (2016)

Correction: Meta-transcriptome Profiling of the Human-Leishmania braziliensis Cutaneous Lesion

Por Christensen, Stephen M., Dillon, Laura A. L., Carvalho, Lucas P., Passos, Sara, Novais, Fernanda O., Hughitt, V. Keith, Beiting, Daniel P., Carvalho, Edgar M., Scott, Phillip, El-Sayed, Najib M., Mosser, David M.
Publicado no PLoS Negl Trop Dis (2017)

Cutaneous leishmaniasis induces a transmissible dysbiotic skin microbiota that promotes skin inflammation

Por Gimblet, Ciara, Meisel, Jacquelyn S., Loesche, Michael A., Cole, Stephen D., Horwinski, Joseph, Novais, Fernanda O., Misic, Ana M., Bradley, Charles W., Beiting, Daniel P., Rankin, Shelley C., Carvalho, Lucas P., Carvalho, Edgar M., Phillip, Scott, Grice, Elizabeth A.
Publicado no Cell Host Microbe (2017)