Aggregate Interactome Based on Protein Cross-linking Interfaces Predicts Drug Targets to Limit Aggregation in Neurodegenerative Diseases

Por Meenakshisundaram Balasubramaniam, Srinivas Ayyadevara, Akshatha Ganne, Samuel Kakraba, Narsimha Reddy Penthala, Xiuxia Du, Peter A. Crooks, Sue T. Griffin, Robert J. Shmookler Reis
Publicado em 2019-10-01

A Novel Microtubule-Binding Drug Attenuates and Reverses Protein Aggregation in Animal Models of Alzheimer’s Disease

Por Samuel Kakraba, Srinivas Ayyadevara, Srinivas Ayyadevara, Narsimha Reddy Penthala, Meenakshisundaram Balasubramaniam, Akshatha Ganne, Ling Liu, Ramani Alla, Ramani Alla, Shoban Babu Bommagani, Steven W. Barger, Steven W. Barger, W. Sue T. Griffin, W. Sue T. Griffin, Peter A. Crooks, Robert J. Shmookler Reis, Robert J. Shmookler Reis, Robert J. Shmookler Reis
Publicado em 2019-12-01