Deep sequencing of the LRRK2 gene in 14,002 individuals reveals evidence of purifying selection and independent origin of the p.Arg1628Pro mutation in Europe

Por Rubio, Justin P., Topp, Simon, Warren, Liling, St Jean, Pamela L., Wegmann, Daniel, Kessner, Darren, Novembre, John, Shen, Judong, Fraser, Dana, Aponte, Jennifer, Nangle, Keith, Cardon, Lon R., Ehm, Margaret G., Chissoe, Stephanie L., Whittaker, John C., Nelson, Matthew R., Mooser, Vincent E.
Publicado em 2012

Deep Resequencing Unveils Genetic Architecture of ADIPOQ and Identifies a Novel Low-Frequency Variant Strongly Associated With Adiponectin Variation

Por Warren, Liling L., Li, Li, Nelson, Matthew R., Ehm, Margaret G., Shen, Judong, Fraser, Dana J., Aponte, Jennifer L., Nangle, Keith L., Slater, Andrew J., Woollard, Peter M., Hall, Matt D., Topp, Simon D., Yuan, Xin, Cardon, Lon R., Chissoe, Stephanie L., Mooser, Vincent, Morris, Andrew D., Palmer, Colin N.A., Perry, John R., Frayling, Timothy M., Whittaker, John C., Waterworth, Dawn M.
Publicado em 2012

An abundance of rare functional variants in 202 drug target genes sequenced in 14,002 people

Por Nelson, Matthew R., Wegmann, Daniel, Ehm, Margaret G., Kessner, Darren, St. Jean, Pamela, Verzilli, Claudio, Shen, Judong, Tang, Zhengzheng, Bacanu, Silviu-Alin, Fraser, Dana, Warren, Liling, Aponte, Jennifer, Zawistowski, Matthew, Liu, Xiao, Zhang, Hao, Zhang, Yong, Li, Jun, Li, Yun, Li, Li, Woollard, Peter, Topp, Simon, Hall, Matthew D., Nangle, Keith, Wang, Jun, Abecasis, Gonçalo, Cardon, Lon R., Zöllner, Sebastian, Whittaker, John C., Chissoe, Stephanie L., Novembre, John, Mooser, Vincent
Publicado no Science (2012)