Antiretroviral activity and pharmacokinetics in mice of oral bis(pivaloyloxymethyl)-9-(2-phosphonylmethoxyethyl)adenine, the bis(pivaloyloxymethyl) ester prodrug of 9-(2-phosphonyl...

Por Naesens, L, Balzarini, J, Bischofberger, N, De Clercq, E
Publicado em 1996

Mouse Adenovirus Type 1 Infection in SCID Mice: an Experimental Model for Antiviral Therapy of Systemic Adenovirus Infections

Por Lenaerts, L., Verbeken, E., De Clercq, E., Naesens, L.
Publicado em 2005

Inhibitory effect of 9-(2-phosphonylmethoxyethyl)adenine on visna virus infection in lambs: a model for in vivo testing of candidate anti-human immunodeficiency virus drugs.

Por Thormar, H, Georgsson, G, Pálsson, P A, Balzarini, J, Naesens, L, Torsteinsdóttir, S, De Clercq, E
Publicado em 1995

Differential antiherpesvirus and antiretrovirus effects of the (S) and (R) enantiomers of acyclic nucleoside phosphonates: potent and selective in vitro and in vivo antiretrovirus...

Por Balzarini, J, Holy, A, Jindrich, J, Naesens, L, Snoeck, R, Schols, D, De Clercq, E
Publicado em 1993

Recovery of Humoral Immunity Is Critical for Successful Antiviral Therapy in Disseminated Mouse Adenovirus Type 1 Infection

Por Lenaerts, L., Kelchtermans, H., Geboes, L., Matthys, P., Verbeken, E., De Clercq, E., Naesens, L.
Publicado em 2008

Mechanism of anti-HIV action of masked alaninyl d4T-MP derivatives.

Por Balzarini, J, Karlsson, A, Aquaro, S, Perno, C F, Cahard, D, Naesens, L, De Clercq, E, McGuigan, C
Publicado em 1996

Antiadenovirus Activities of Several Classes of Nucleoside and Nucleotide Analogues

Por Naesens, L., Lenaerts, L., Andrei, G., Snoeck, R., Van Beers, D., Holý, Antonin, Balzarini, Jan, De Clercq, Erik
Publicado em 2005

Marked in vivo antiretrovirus activity of 9-(2-phosphonylmethoxyethyl)adenine, a selective anti-human immunodeficiency virus agent.

Por Balzarini, J, Naesens, L, Herdewijn, P, Rosenberg, I, Holy, A, Pauwels, R, Baba, M, Johns, D G, De Clercq, E
Publicado em 1989

(R)-9-(2-phosphonylmethoxypropyl)-2,6-diaminopurine is a potent inhibitor of feline immunodeficiency virus infection.

Por Vahlenkamp, T W, De Ronde, A, Balzarini, J, Naesens, L, De Clercq, E, van Eijk, M J, Horzinek, M C, Egberink, H F
Publicado em 1995