Projecting human pharmacokinetics of therapeutic antibodies from nonclinical data: What have we learned?

Por Deng, Rong, Iyer, Suhasini, Theil, Frank-Peter, Mortensen, Deborah L, Fielder, Paul J, Prabhu, Saileta
Publicado em 2011

Effect of antigen binding affinity and effector function on the pharmacokinetics and pharmacodynamics of anti-IgE monoclonal antibodies

Por Mortensen, Deborah L., Prabhu, Saileta, Stefanich, Eric G., Kadkhodayan-Fischer, Saloumeh, Gelzleichter, Thomas R., Baker, Dana, Jiang, Jenny, Wallace, Kristin, Iyer, Suhasini, Fielder, Paul J., Putnam, Wendy S.
Publicado em 2012