Predicting Potential Endocrine Disrupting Chemicals Binding to Estrogen Receptor α (ERα) Using a Pipeline Combining Structure-Based and Ligand-Based in Silico Methods

by Sellami, Asma, Montes, Matthieu, Lagarde, Nathalie
Published in Int J Mol Sci (2021)

Discriminating agonist and antagonist ligands of the nuclear receptors using 3D-pharmacophores

by Lagarde, Nathalie, Delahaye, Solenne, Zagury, Jean-François, Montes, Matthieu
Published in J Cheminform (2016)

Hits Discovery on the Androgen Receptor: In Silico Approaches to Identify Agonist Compounds

by Réau, Manon, Lagarde, Nathalie, Zagury, Jean-François, Montes, Matthieu
Published in Cells (2019)

Decoys Selection in Benchmarking Datasets: Overview and Perspectives

by Réau, Manon, Langenfeld, Florent, Zagury, Jean-François, Lagarde, Nathalie, Montes, Matthieu
Published in Front Pharmacol (2018)

FAF-Drugs: free ADME/tox filtering of compound collections

by Miteva, Maria A., Violas, Stephanie, Montes, Matthieu, Gomez, David, Tuffery, Pierre, Villoutreix, Bruno O.
Published 2006

Predictiveness curves in virtual screening

by Empereur-mot, Charly, Guillemain, Hélène, Latouche, Aurélien, Zagury, Jean-François, Viallon, Vivian, Montes, Matthieu
Published in J Cheminform (2015)

Immunization against an IL-6 peptide induces anti-IL-6 antibodies and modulates the Delayed-Type Hypersensitivity reaction in cynomolgus monkeys

by Desallais, Lucille, Bouchez, Caroline, Mouhsine, Hadley, Moreau, Gabriel, Ratsimandresy, Rojo, Montes, Matthieu, Do, Hervé, Quintin-Colonna, Françoise, Zagury, Jean-François
Published in Sci Rep (2016)

Targeting IL-6 by both passive or active immunization strategies prevents bleomycin-induced skin fibrosis

by Desallais, Lucille, Avouac, Jérôme, Fréchet, Maxime, Elhai, Muriel, Ratsimandresy, Rojo, Montes, Matthieu, Mouhsine, Hadley, Do, Hervé, Zagury, Jean-François, Allanore, Yannick
Published in Arthritis Res Ther (2014)

High-resolution mining of the SARS-CoV-2 main protease conformational space: supercomputer-driven unsupervised adaptive sampling

by Jaffrelot Inizan, Théo, Célerse, Frédéric, Adjoua, Olivier, El Ahdab, Dina, Jolly, Luc-Henri, Liu, Chengwen, Ren, Pengyu, Montes, Matthieu, Lagarde, Nathalie, Lagardère, Louis, Monmarché, Pierre, Piquemal, Jean-Philip
Published in Chem Sci (2021)

Identification of Genes Whose Expression Profile Is Associated with Non-Progression towards AIDS Using eQTLs

by Spadoni, Jean-Louis, Rucart, Pierre, Le Clerc, Sigrid, van Manen, Daniëlle, Coulonges, Cédric, Ulveling, Damien, Laville, Vincent, Labib, Taoufik, Taing, Lieng, Delaneau, Olivier, Montes, Matthieu, Schuitemaker, Hanneke, Noirel, Josselin, Zagury, Jean-François
Published in PLoS One (2015)

Neuropilin 1 and Neuropilin 2 gene invalidation or pharmacological inhibition reveals their relevance for the treatment of metastatic renal cell carcinoma

by Dumond, Aurore, Brachet, Etienne, Durivault, Jérôme, Vial, Valérie, Puszko, Anna K., Lepelletier, Yves, Montemagno, Christopher, Pagnuzzi-Boncompagni, Marina, Hermine, Olivier, Garbay, Christiane, Lagarde, Nathalie, Montes, Matthieu, Demange, Luc, Grépin, Renaud, Pagès, Gilles
Published in J Exp Clin Cancer Res (2021)

New CXCR1/CXCR2 inhibitors represent an effective treatment for kidney or head and neck cancers sensitive or refractory to reference treatments

by Dufies, Maeva, Grytsai, Oleksandr, Ronco, Cyril, Camara, Oumar, Ambrosetti, Damien, Hagege, Anaïs, Parola, Julien, Mateo, Lou, Ayrault, Marion, Giuliano, Sandy, Grépin, Renaud, Lagarde, Nathalie, Montes, Matthieu, Auberger, Patrick, Demange, Luc, Benhida, Rachid, Pagès, Gilles
Published in Theranostics (2019)

Identification of an in vivo orally active dual-binding protein-protein interaction inhibitor targeting TNFα through combined in silico/in vitro/in vivo screening

by Mouhsine, Hadley, Guillemain, Hélène, Moreau, Gabriel, Fourati, Najla, Zerrouki, Chouki, Baron, Bruno, Desallais, Lucille, Gizzi, Patrick, Ben Nasr, Nesrine, Perrier, Julie, Ratsimandresy, Rojo, Spadoni, Jean-Louis, Do, Hervé, England, Patrick, Montes, Matthieu, Zagury, Jean-François
Published in Sci Rep (2017)

SCREENING LOW FREQUENCY SNPS FROM GENOME WIDE ASSOCIATION STUDY REVEALS A NEW RISK ALLELE FOR PROGRESSION TO AIDS

by Le Clerc, Sigrid, Coulonges, Cédric, Delaneau, Olivier, Van Manen, Danielle, Herbeck, Joshua T., Limou, Sophie, An, Ping, Martinson, Jeremy J., Spadoni, Jean-Louis, Therwath, Amu, Veldink, Jan H., van den Berg, Leonard H., Taing, Lieng, Labib, Taoufik, Mellak, Safa, Montes, Matthieu, Delfraissy, Jean-François, Schächter, François, Winkler, Cheryl, Froguel, Philippe, Mullins, James I., Schuitemaker, Hanneke, Zagury, Jean-François
Published 2011

Multicohort Genomewide Association Study Reveals a New Signal of Protection Against HIV-1 Acquisition

by Limou, Sophie, Delaneau, Olivier, van Manen, Daniëlle, An, Ping, Sezgin, Efe, Le Clerc, Sigrid, Coulonges, Cédric, Troyer, Jennifer L., Veldink, Jan H., van den Berg, Leonard H., Spadoni, Jean-Louis, Taing, Lieng, Labib, Taoufik, Montes, Matthieu, Delfraissy, Jean-François, Schachter, François, O’Brien, Stephen J., Buchbinder, Susan, van Natta, Mark L., Jabs, Douglas A., Froguel, Philippe, Schuitemaker, Hanneke, Winkler, Cheryl A., Zagury, Jean-François
Published 2012

Multiple-cohort genetic association study reveals CXCR6 as a new chemokine receptor involved in long-term nonprogression to AIDS

by Limou, Sophie, Coulonges, Cédric, Herbeck, Joshua T., van Manen, Daniëlle, An, Ping, Le Clerc, Sigrid, Delaneau, Olivier, Diop, Gora, Taing, Lieng, Montes, Matthieu, van't Wout, Angélique B., Gottlieb, Geoffrey S., Therwath, Amu, Rouzioux, Christine, Delfraissy, Jean-François, Lelièvre, Jean-Daniel, Lévy, Yves, Hercberg, Serge, Dina, Christian, Phair, John, Donfield, Sharyne, Goedert, James J., Buchbinder, Susan, Estaquier, Jérôme, Schächter, François, Gut, Ivo, Froguel, Philippe, Mullins, James I., Schuitemaker, Hanneke, Winkler, Cheryl, Zagury, Jean-François
Published 2010