The potential of carboxypeptidase G2: antibody conjugates as anti-tumour agents. II. In vivo localising and clearance properties in a choriocarcinoma model.

Por Melton, R. G., Searle, F., Sherwood, R. F., Bagshawe, K. D., Boden, J. A.
Publicado em 1990

Galactosylated streptavidin for improved clearance of biotinylated intact and F(ab')2 fragments of an anti-tumour antibody.

Por Marshall, D., Pedley, R. B., Melton, R. G., Boden, J. A., Boden, R., Begent, R. H.
Publicado em 1995

Polyethylene glycol modification of a galactosylated streptavidin clearing agent: effects on immunogenicity and clearance of a biotinylated anti-tumour antibody.

Por Marshall, D., Pedley, R. B., Boden, J. A., Boden, R., Melton, R. G., Begent, R. H.
Publicado em 1996

Carboxypeptidase G(2) rescue in patients with methotrexate intoxication and renal failure

Por Buchen, S, Ngampolo, D, Melton, R G, Hasan, C, Zoubek, A, Henze, G, Bode, U, Fleischhack, G
Publicado em 2005

A cytotoxic agent can be generated selectively at cancer sites.

Por Bagshawe, K. D., Springer, C. J., Searle, F., Antoniw, P., Sharma, S. K., Melton, R. G., Sherwood, R. F.
Publicado em 1988

Disposition of the prodrug 4-(bis (2-chloroethyl) amino) benzoyl-L-glutamic acid and its active parent drug in mice.

Por Antoniw, P., Springer, C. J., Bagshawe, K. D., Searle, F., Melton, R. G., Rogers, G. T., Burke, P. J., Sherwood, R. F.
Publicado em 1990

The potential of carboxypeptidase G2-antibody conjugates as anti-tumour agents. I. Preparation of antihuman chorionic gonadotrophin-carboxypeptidase G2 and cytotoxicity of the conj...

Por Searle, F., Bier, C., Buckley, R. G., Newman, S., Pedley, R. B., Bagshawe, K. D., Melton, R. G., Alwan, S. M., Sherwood, R. F.
Publicado em 1986

Anti-tumour effects of an antibody-carboxypeptidase G2 conjugate in combination with phenol mustard prodrugs.

Por Blakey, D. C., Davies, D. H., Dowell, R. I., East, S. J., Burke, P. J., Sharma, S. K., Springer, C. J., Mauger, A. B., Melton, R. G.
Publicado em 1995