Current progress in Structure-Based Rational Drug Design marks a new mindset in drug discovery

Por Lounnas, Valère, Ritschel, Tina, Kelder, Jan, McGuire, Ross, Bywater, Robert P., Foloppe, Nicolas
Publicado em 2013

3D-e-Chem-VM: Structural Cheminformatics Research Infrastructure in a Freely Available Virtual Machine

Por McGuire, Ross, Verhoeven, Stefan, Vass, Márton, Vriend, Gerrit, de Esch, Iwan J. P., Lusher, Scott J., Leurs, Rob, Ridder, Lars, Kooistra, Albert J., Ritschel, Tina, de Graaf, Chris
Publicado no J Chem Inf Model (2017)

X-ray Structures of Progesterone Receptor Ligand Binding Domain in Its Agonist State Reveal Differing Mechanisms for Mixed Profiles of 11β-Substituted Steroids

Por Lusher, Scott J., Raaijmakers, Hans C. A., Vu-Pham, Diep, Kazemier, Bert, Bosch, Rolien, McGuire, Ross, Azevedo, Rita, Hamersma, Hans, Dechering, Koen, Oubrie, Arthur, van Duin, Marcel, de Vlieg, Jacob
Publicado em 2012

Structural Basis for Agonism and Antagonism for a Set of Chemically Related Progesterone Receptor Modulators

Por Lusher, Scott J., Raaijmakers, Hans C. A., Vu-Pham, Diep, Dechering, Koen, Lam, Tsang Wai, Brown, Angus R., Hamilton, Niall M., Nimz, Olaf, Bosch, Rolien, McGuire, Ross, Oubrie, Arthur, de Vlieg, Jacob
Publicado em 2011

Org 214007-0: A Novel Non-Steroidal Selective Glucocorticoid Receptor Modulator with Full Anti-Inflammatory Properties and Improved Therapeutic Index

Por van Lierop, Marie-José C., Alkema, Wynand, Laskewitz, Anke J., Dijkema, Rein, van der Maaden, Hans M., Smit, Martin J., Plate, Ralf, Conti, Paolo G. M., Jans, Christan G. J. M., Timmers, C. Marco, van Boeckel, Constant A. A., Lusher, Scott J., McGuire, Ross, van Schaik, Rene C., de Vlieg, Jacob, Smeets, Ruben L., Hofstra, Claudia L., Boots, Annemieke M. H., van Duin, Marcel, Ingelse, Benno A., Schoonen, Willem G. E. J., Grefhorst, Aldo, van Dijk, Theo H., Kuipers, Folkert, Dokter, Wim H. A.
Publicado em 2012