Characterization of two novel intronic OPA1 mutations resulting in aberrant pre-mRNA splicing

di Bolognini, Ramona, Gerth-Kahlert, Christina, Abegg, Mathias, Bartholdi, Deborah, Mathis, Nicolas, Sturm, Veit, Gallati, Sabina, Schaller, André
Pubblicato in BMC Med Genet (2017)

Predicting prime editing efficiency and product purity by deep learning

di Mathis, Nicolas, Allam, Ahmed, Kissling, Lucas, Marquart, Kim Fabiano, Schmidheini, Lukas, Solari, Cristina, Balázs, Zsolt, Krauthammer, Michael, Schwank, Gerald
Pubblicato in Nat Biotechnol (2023)

A paracrine activin A–mDia2 axis promotes squamous carcinogenesis via fibroblast reprogramming

di Cangkrama, Michael, Wietecha, Mateusz, Mathis, Nicolas, Okumura, Rin, Ferrarese, Luca, Al‐Nuaimi, Dunja, Antsiferova, Maria, Dummer, Reinhard, Innocenti, Metello, Werner, Sabine
Pubblicato in EMBO Mol Med (2020)

Continuous directed evolution of a compact CjCas9 variant with broad PAM compatibility

di Schmidheini, Lukas, Mathis, Nicolas, Marquart, Kim Fabiano, Rothgangl, Tanja, Kissling, Lucas, Böck, Desirée, Chanez, Christelle, Wang, Jingrui Priscilla, Jinek, Martin, Schwank, Gerald
Pubblicato in Nat Chem Biol (2024)

In vivo prime editing of a metabolic liver disease in mice

di Böck, Desirée, Rothgangl, Tanja, Villiger, Lukas, Schmidheini, Lukas, Matsushita, Mai, Mathis, Nicolas, Ioannidi, Eleonora, Rimann, Nicole, Grisch-Chan, Hiu Man, Kreutzer, Susanne, Kontarakis, Zacharias, Kopf, Manfred, Thöny, Beat, Schwank, Gerald
Pubblicato in Sci Transl Med (2022)