NKp44 and Natural Cytotoxicity Receptors as Damage-Associated Molecular Pattern Recognition Receptors

Por Horton, Nathan C., Mathew, Porunelloor A.
Publicado no Front Immunol (2015)

CS1 (SLAMF7, CD319) is an effective immunotherapeutic target for multiple myeloma

Por Malaer, Joseph D, Mathew, Porunelloor A
Publicado no Am J Cancer Res (2017)

Protein kinase C is involved in 2B4 (CD244)-mediated cytotoxicity and AP-1 activation in natural killer cells

Por Chuang, Samuel S, Lee, Jae-Kyung, Mathew, Porunelloor A
Publicado em 2003

Novel Interaction between Proliferating Cell Nuclear Antigen and HLA I on the Surface of Tumor Cells Inhibits NK Cell Function through NKp44

Por Horton, Nathan C., Mathew, Stephen O., Mathew, Porunelloor A.
Publicado em 2013

Human natural killer cell receptor 2B4 (CD244) down-regulates its own expression by reduced promoter activity at an Ets element

Por Mathew, Stephen O., Vaidya, Swapnil V., Kim, Jong R., Mathew, Porunelloor A.
Publicado em 2007

2B4(+)CD8(+) T cells play an inhibitory role against constrained HIV Epitopes

Por Aldy, Kim N., Horton, Nathan C., Mathew, Porunelloor A., Mathew, Stephen O.
Publicado em 2011

Absence of mouse 2B4 promotes NK cell–mediated killing of activated CD8(+) T cells, leading to prolonged viral persistence and altered pathogenesis

Por Waggoner, Stephen N., Taniguchi, Ruth T., Mathew, Porunelloor A., Kumar, Vinay, Welsh, Raymond M.
Publicado em 2010

A novel ligand on astrocytes interacts with natural cytotoxicity receptor NKp44 regulating immune response mediated by NK cells

Por Bowen, Kelly E., Mathew, Stephen O., Borgmann, Kathleen, Ghorpade, Anuja, Mathew, Porunelloor A.
Publicado no PLoS One (2018)

Overexpression of LLT1 (OCIL, CLEC2D) on prostate cancer cells inhibits NK cell-mediated killing through LLT1-NKRP1A (CD161) interaction

Por Mathew, Stephen O., Chaudhary, Pankaj, Powers, Sheila B., Vishwanatha, Jamboor K., Mathew, Porunelloor A.
Publicado no Oncotarget (2016)

Characterization of inhibitory and stimulatory forms of the murine natural killer cell receptor 2B4

Por Schatzle, John D., Sheu, Shane, Stepp, Susan E., Mathew, Porunelloor A., Bennett, Michael, Kumar, Vinay
Publicado em 1999

Blocking LLT1 (CLEC2D, OCIL)-NKRP1A (CD161) interaction enhances natural killer cell-mediated lysis of triple-negative breast cancer cells

Por Marrufo, Armando M, Mathew, Stephen O, Chaudhary, Pankaj, Malaer, Joseph D, Vishwanatha, Jamboor K, Mathew, Porunelloor A
Publicado no Am J Cancer Res (2018)

2B4, the Natural Killer and T Cell Immunoglobulin Superfamily Surface Protein, Is a Ligand for CD48

Por Brown, Marion H., Boles, Kent, Anton van der Merwe, P., Kumar, Vinay, Mathew, Porunelloor A., Neil Barclay, A.
Publicado em 1998

2B4 Acts As a Non–Major Histocompatibility Complex Binding Inhibitory Receptor on Mouse Natural Killer Cells

Por Lee, Kyung-Mi, McNerney, Megan E., Stepp, Susan E., Mathew, Porunelloor A., Schatzle, John D., Bennett, Michael, Kumar, Vinay
Publicado em 2004

Requirement of homotypic NK-cell interactions through 2B4(CD244)/CD48 in the generation of NK effector functions

Por Lee, Kyung-Mi, Forman, John P., McNerney, Megan E., Stepp, Susan, Kuppireddi, Sumalatha, Guzior, Dustin, Latchman, Yvette E., Sayegh, Mohamed H., Yagita, Hideo, Park, Chul-Kyu, Oh, Seog Bae, Wülfing, Christoph, Schatzle, John, Mathew, Porunelloor A., Sharpe, Arlene H., Kumar, Vinay
Publicado em 2006