Treating SCA1 Mice with Water-Soluble Compounds to Non-Specifically Boost Mitochondrial Function

por Ferro, Austin, Carbone, Emily, Marzouk, Evan, Siegel, Asher, Nguyen, Donna, Polley, Kailen, Hartman, Jessilyn, Frederick, Kimberley, Ives, Stephen, Lagalwar, Sarita
Publicado no J Vis Exp (2017)

Short-term succinic acid treatment mitigates cerebellar mitochondrial OXPHOS dysfunction, neurodegeneration and ataxia in a Purkinje-specific spinocerebellar ataxia type 1 (SCA1) m...

por Ferro, Austin, Carbone, Emily, Zhang, Jenny, Marzouk, Evan, Villegas, Monica, Siegel, Asher, Nguyen, Donna, Possidente, Thomas, Hartman, Jessilyn, Polley, Kailen, Ingram, Melissa A., Berry, Georgia, Reynolds, Thomas H., Possidente, Bernard, Frederick, Kimberley, Ives, Stephen, Lagalwar, Sarita
Publicado no PLoS One (2017)