Treating SCA1 Mice with Water-Soluble Compounds to Non-Specifically Boost Mitochondrial Function

by Ferro, Austin, Carbone, Emily, Marzouk, Evan, Siegel, Asher, Nguyen, Donna, Polley, Kailen, Hartman, Jessilyn, Frederick, Kimberley, Ives, Stephen, Lagalwar, Sarita
Published in J Vis Exp (2017)

Short-term succinic acid treatment mitigates cerebellar mitochondrial OXPHOS dysfunction, neurodegeneration and ataxia in a Purkinje-specific spinocerebellar ataxia type 1 (SCA1) m...

by Ferro, Austin, Carbone, Emily, Zhang, Jenny, Marzouk, Evan, Villegas, Monica, Siegel, Asher, Nguyen, Donna, Possidente, Thomas, Hartman, Jessilyn, Polley, Kailen, Ingram, Melissa A., Berry, Georgia, Reynolds, Thomas H., Possidente, Bernard, Frederick, Kimberley, Ives, Stephen, Lagalwar, Sarita
Published in PLoS One (2017)