Treating SCA1 Mice with Water-Soluble Compounds to Non-Specifically Boost Mitochondrial Function

par Ferro, Austin, Carbone, Emily, Marzouk, Evan, Siegel, Asher, Nguyen, Donna, Polley, Kailen, Hartman, Jessilyn, Frederick, Kimberley, Ives, Stephen, Lagalwar, Sarita
Publié dans J Vis Exp (2017)

Short-term succinic acid treatment mitigates cerebellar mitochondrial OXPHOS dysfunction, neurodegeneration and ataxia in a Purkinje-specific spinocerebellar ataxia type 1 (SCA1) m...

par Ferro, Austin, Carbone, Emily, Zhang, Jenny, Marzouk, Evan, Villegas, Monica, Siegel, Asher, Nguyen, Donna, Possidente, Thomas, Hartman, Jessilyn, Polley, Kailen, Ingram, Melissa A., Berry, Georgia, Reynolds, Thomas H., Possidente, Bernard, Frederick, Kimberley, Ives, Stephen, Lagalwar, Sarita
Publié dans PLoS One (2017)