Treating SCA1 Mice with Water-Soluble Compounds to Non-Specifically Boost Mitochondrial Function

Autor Ferro, Austin, Carbone, Emily, Marzouk, Evan, Siegel, Asher, Nguyen, Donna, Polley, Kailen, Hartman, Jessilyn, Frederick, Kimberley, Ives, Stephen, Lagalwar, Sarita
Vydáno v J Vis Exp (2017)

Short-term succinic acid treatment mitigates cerebellar mitochondrial OXPHOS dysfunction, neurodegeneration and ataxia in a Purkinje-specific spinocerebellar ataxia type 1 (SCA1) m...

Autor Ferro, Austin, Carbone, Emily, Zhang, Jenny, Marzouk, Evan, Villegas, Monica, Siegel, Asher, Nguyen, Donna, Possidente, Thomas, Hartman, Jessilyn, Polley, Kailen, Ingram, Melissa A., Berry, Georgia, Reynolds, Thomas H., Possidente, Bernard, Frederick, Kimberley, Ives, Stephen, Lagalwar, Sarita
Vydáno v PLoS One (2017)