High and low mutational burden tumors versus immunologically hot and cold tumors and response to immune checkpoint inhibitors

por Maleki Vareki, Saman
Publicado en J Immunother Cancer (2018)

Immunosuppressive Effects of Myeloid-Derived Suppressor Cells in Cancer and Immunotherapy

por Krishnamoorthy, Mithunah, Gerhardt, Lara, Maleki Vareki, Saman
Publicado en Cells (2021)

Neoadjuvant Immunotherapy for High-Risk, Resectable Malignancies: Scientific Rationale and Clinical Challenges

por Krishnamoorthy, Mithunah, Lenehan, John G, Maleki Vareki, Saman
Publicado en J Natl Cancer Inst (2021)

Novel anti-cancer drug COTI-2 synergizes with therapeutic agents and does not induce resistance or exhibit cross-resistance in human cancer cell lines

por Maleki Vareki, Saman, Salim, Kowthar Y., Danter, Wayne R., Koropatnick, James
Publicado en PLoS One (2018)

Immunomodulation in Pancreatic Cancer

por Krishnamoorthy, Mithunah, Lenehan, John G., Burton, Jeremy P., Maleki Vareki, Saman
Publicado en Cancers (Basel) (2020)

Treatment-naïve HPV+ head and neck cancers display a T-cell-inflamed phenotype distinct from their HPV- counterparts that has implications for immunotherapy

por Gameiro, Steven F., Ghasemi, Farhad, Barrett, John W., Koropatnick, James, Nichols, Anthony C., Mymryk, Joe S., Maleki Vareki, Saman
Publicado en Oncoimmunology (2018)

The role of gut microbiome in modulating response to immune checkpoint inhibitor therapy in cancer

por Naqash, Abdul Rafeh, Kihn-Alarcón, Alba J., Stavraka, Chara, Kerrigan, Kathleen, Maleki Vareki, Saman, Pinato, David James, Puri, Sonam
Publicado en Ann Transl Med (2021)

IDO Downregulation Induces Sensitivity to Pemetrexed, Gemcitabine, FK866, and Methoxyamine in Human Cancer Cells

por Maleki Vareki, Saman, Chen, Di, Di Cresce, Christine, Ferguson, Peter J., Figueredo, Rene, Pampillo, Macarena, Rytelewski, Mateusz, Vincent, Mark, Min, Weiping, Zheng, Xiufen, Koropatnick, James
Publicado en PLoS One (2015)

BMI, irAE, and gene expression signatures associate with resistance to immune-checkpoint inhibition and outcomes in renal cell carcinoma

por Labadie, Brian W., Liu, Ping, Bao, Riyue, Crist, Michael, Fernandes, Ricardo, Ferreira, Laura, Graupner, Scott, Poklepovic, Andrew S., Duran, Ignacio, Maleki Vareki, Saman, Balar, Arjun V., Luke, Jason J.
Publicado en J Transl Med (2019)

Differential regulation of simultaneous anti-tumor and alloreactive CD8(+) T cell responses in the same host by rapamycin

por Maleki Vareki, S., Harding, M.J., Waithman, J., Zanker, D., Shivji, A.N., Rytelewski, M., Mazzuca, D.M., Yekta, M.A., Chen, W., Schell, T.D., Haeryfar, S.M.M.
Publicado 2011

BRCA2 inhibition enhances cisplatin‐mediated alterations in tumor cell proliferation, metabolism, and metastasis

por Rytelewski, Mateusz, Tong, Jessica G., Buensuceso, Adrian, Leong, Hon S., Maleki Vareki, Saman, Figueredo, Rene, Di Cresce, Christine, Wu, Sherry Y., Herbrich, Shelley M., Baggerly, Keith A., Romanow, Larissa, Shepherd, Trevor, Deroo, Bonnie J., Sood, Anil K., Chambers, Ann F., Vincent, Mark, Ferguson, Peter J., Koropatnick, James
Publicado en Mol Oncol (2014)