The future is now for rare genetic diseases

Autor MacKenzie, Alex, Boycott, Kym M.
Vydáno 2012

Current and emerging treatment options for spinal muscular atrophy

Autor Farooq, Faraz, MacKenzie, Alex E
Vydáno v Degener Neurol Neuromuscul Dis (2015)

Separating the Wheat from the Chaff: The Use of Upstream Regulator Analysis to Identify True Differential Expression of Single Genes within Transcriptomic Datasets

Autor Hadwen, Jeremiah, Schock, Sarah, Farooq, Faraz, MacKenzie, Alex, Plaza-Diaz, Julio
Vydáno v Int J Mol Sci (2021)

Anisomycin Activates Utrophin Upregulation Through a p38 Signaling Pathway

Autor Hadwen, Jeremiah, Farooq, Faraz, Witherspoon, Luke, Schock, Sarah, Mongeon, Kevin, MacKenzie, Alex
Vydáno v Clin Transl Sci (2018)

Estrogen Suppresses Uterine Epithelial Apoptosis by Inducing Birc1 Expression

Autor Yin, Yan, Huang, Wei-Wei, Lin, Congxing, Chen, Hong, MacKenzie, Alex, Ma, Liang
Vydáno 2008

Sodium Channel Inhibitors Reduce DMPK mRNA and Protein

Autor Witherspoon, Luke, O'Reilly, Sean, Hadwen, Jeremiah, Tasnim, Nafisa, MacKenzie, Alex, Farooq, Faraz
Vydáno v Clin Transl Sci (2015)

CHRIMCY: A proposed institute for research on reproduction, development, and mother, child and youth health

Autor Guyda, Harvey, Armstrong, Robert, Milne, Ken, MacKenzie, Alex, Han, Victor, Bortolussi, Robert, Orrbine, Elaine
Vydáno 2000

The hippocampal neurons of neuronal apoptosis inhibitory protein 1 (NAIP1)-deleted mice display increased vulnerability to kainic acid-induced injury

Autor Holcik, Martin, Thompson, Charlie S., Yaraghi, Zahra, Lefebvre, Charles A., MacKenzie, Alex E., Korneluk, Robert G.
Vydáno 2000

VPAC2 receptor agonist BAY 55-9837 increases SMN protein levels and moderates disease phenotype in severe spinal muscular atrophy mouse models

Autor Hadwen, Jeremiah, MacKenzie, Duncan, Shamim, Fahad, Mongeon, Kevin, Holcik, Martin, MacKenzie, Alex, Farooq, Faraz
Vydáno 2014

Neuronal apoptosis inhibitory protein (NAIP) localizes to the cytokinetic machinery during cell division

Autor Abadía-Molina, Francisco, Morón-Calvente, Virginia, Baird, Stephen D., Shamim, Fahad, Martín, Francisco, MacKenzie, Alex
Vydáno v Sci Rep (2017)

Mining the transcriptome for rare disease therapies: a comparison of the efficiencies of two data mining approaches and a targeted cell-based drug screen

Autor Mears, A. J., Schock, S. C., Hadwen, J., Putos, S., Dyment, D., Boycott, K. M., MacKenzie, Alex
Vydáno v NPJ Genom Med (2017)

Prolactin increases SMN expression and survival in a mouse model of severe spinal muscular atrophy via the STAT5 pathway

Autor Farooq, Faraz, Molina, Francisco Abadía, Hadwen, Jeremiah, MacKenzie, Duncan, Witherspoon, Luke, Osmond, Matthew, Holcik, Martin, MacKenzie, Alex
Vydáno 2011

Prolactin increases SMN expression and survival in a mouse model of severe spinal muscular atrophy via the STAT5 pathway

Autor Farooq, Faraz, Molina, Francisco Abadía, Hadwen, Jeremiah, MacKenzie, Duncan, Witherspoon, Luke, Osmond, Matthew, Holcik, Martin, MacKenzie, Alex
Vydáno 2011

Motoneuron Resistance to Apoptotic Cell Death In Vivo Correlates with the Ratio between X-Linked Inhibitor of Apoptosis Proteins (XIAPs) and Its Inhibitor, XIAP-Associated Factor 1

Autor Perrelet, Daniel, Perrin, Florence E., Liston, Peter, Korneluk, Robert G., MacKenzie, Alex, Ferrer-Alcon, Marcel, Kato, Ann C.
Vydáno v J Neurosci (2004)

High-throughput DNA Extraction and Genotyping of 3dpf Zebrafish Larvae by Fin Clipping

Autor Kosuta, Ceres, Daniel, Kate, Johnstone, Devon L., Mongeon, Kevin, Ban, Kevin, LeBlanc, Sophie, MacLeod, Stuart, Et-Tahiry, Karim, Ekker, Marc, MacKenzie, Alex, Pena, Izabella
Vydáno v J Vis Exp (2018)

The Neuronal Apoptosis Inhibitory Protein Is a Direct Inhibitor of Caspases 3 and 7

Autor Maier, Johannes K. X., Lahoua, Zahia, Gendron, Nathalie H., Fetni, Raouf, Johnston, Anne, Davoodi, Jamshid, Rasper, Dita, Roy, Sophie, Slack, Ruth S., Nicholson, Donald W., MacKenzie, Alex E.
Vydáno v J Neurosci (2002)

A generalizable pre-clinical research approach for orphan disease therapy

Autor Beaulieu Chandree L, Samuels Mark E, Ekins Sean, McMaster Christopher R, Edwards Aled M, Krainer Adrian R, Hicks Geoffrey G, Frey Brendan J, Boycott Kym M, MacKenzie Alex E
Vydáno 2012-06-01

A generalizable pre-clinical research approach for orphan disease therapy

Autor Beaulieu, Chandree L, Samuels, Mark E, Ekins, Sean, McMaster, Christopher R, Edwards, Aled M, Krainer, Adrian R, Hicks, Geoffrey G, Frey, Brendan J, Boycott, Kym M, MacKenzie, Alex E
Vydáno 2012

The human ryanodine receptor gene: Its mapping to 19q13.1, placement in a chromosome 19 linkage group, and exclusion as the gene causing myotonic dystrophy

Autor MacKenzie, Alex E., Korneluk, Robert G., Zorzato, Francesco, Fujii, Junichi, Phillips, Michael, Iles, David, Wieringa, Bé, Leblond, Suzanne, Bailly, Jane, Willard, Huntington F., Duff, Catherine, Worton, Ronald G., MacLennan, David H.
Vydáno 1990

Inhibitor of apoptosis proteins, NAIP, cIAP1 and cIAP2 expression during macrophage differentiation and M1/M2 polarization

Autor Morón-Calvente, Virginia, Romero-Pinedo, Salvador, Toribio-Castelló, Sofía, Plaza-Díaz, Julio, Abadía-Molina, Ana C., Rojas-Barros, Domingo I., Beug, Shawn T., LaCasse, Eric C., MacKenzie, Alex, Korneluk, Robert, Abadía-Molina, Francisco
Vydáno v PLoS One (2018)