The future is now for rare genetic diseases

av MacKenzie, Alex, Boycott, Kym M.
Publicerad 2012

Current and emerging treatment options for spinal muscular atrophy

av Farooq, Faraz, MacKenzie, Alex E
I publikationen Degener Neurol Neuromuscul Dis (2015)

Separating the Wheat from the Chaff: The Use of Upstream Regulator Analysis to Identify True Differential Expression of Single Genes within Transcriptomic Datasets

av Hadwen, Jeremiah, Schock, Sarah, Farooq, Faraz, MacKenzie, Alex, Plaza-Diaz, Julio
I publikationen Int J Mol Sci (2021)

Anisomycin Activates Utrophin Upregulation Through a p38 Signaling Pathway

av Hadwen, Jeremiah, Farooq, Faraz, Witherspoon, Luke, Schock, Sarah, Mongeon, Kevin, MacKenzie, Alex
I publikationen Clin Transl Sci (2018)

Estrogen Suppresses Uterine Epithelial Apoptosis by Inducing Birc1 Expression

av Yin, Yan, Huang, Wei-Wei, Lin, Congxing, Chen, Hong, MacKenzie, Alex, Ma, Liang
Publicerad 2008

Sodium Channel Inhibitors Reduce DMPK mRNA and Protein

av Witherspoon, Luke, O'Reilly, Sean, Hadwen, Jeremiah, Tasnim, Nafisa, MacKenzie, Alex, Farooq, Faraz
I publikationen Clin Transl Sci (2015)

CHRIMCY: A proposed institute for research on reproduction, development, and mother, child and youth health

av Guyda, Harvey, Armstrong, Robert, Milne, Ken, MacKenzie, Alex, Han, Victor, Bortolussi, Robert, Orrbine, Elaine
Publicerad 2000

The hippocampal neurons of neuronal apoptosis inhibitory protein 1 (NAIP1)-deleted mice display increased vulnerability to kainic acid-induced injury

av Holcik, Martin, Thompson, Charlie S., Yaraghi, Zahra, Lefebvre, Charles A., MacKenzie, Alex E., Korneluk, Robert G.
Publicerad 2000

VPAC2 receptor agonist BAY 55-9837 increases SMN protein levels and moderates disease phenotype in severe spinal muscular atrophy mouse models

av Hadwen, Jeremiah, MacKenzie, Duncan, Shamim, Fahad, Mongeon, Kevin, Holcik, Martin, MacKenzie, Alex, Farooq, Faraz
Publicerad 2014

Neuronal apoptosis inhibitory protein (NAIP) localizes to the cytokinetic machinery during cell division

av Abadía-Molina, Francisco, Morón-Calvente, Virginia, Baird, Stephen D., Shamim, Fahad, Martín, Francisco, MacKenzie, Alex
I publikationen Sci Rep (2017)

Mining the transcriptome for rare disease therapies: a comparison of the efficiencies of two data mining approaches and a targeted cell-based drug screen

av Mears, A. J., Schock, S. C., Hadwen, J., Putos, S., Dyment, D., Boycott, K. M., MacKenzie, Alex
I publikationen NPJ Genom Med (2017)

Prolactin increases SMN expression and survival in a mouse model of severe spinal muscular atrophy via the STAT5 pathway

av Farooq, Faraz, Molina, Francisco Abadía, Hadwen, Jeremiah, MacKenzie, Duncan, Witherspoon, Luke, Osmond, Matthew, Holcik, Martin, MacKenzie, Alex
Publicerad 2011

Prolactin increases SMN expression and survival in a mouse model of severe spinal muscular atrophy via the STAT5 pathway

av Farooq, Faraz, Molina, Francisco Abadía, Hadwen, Jeremiah, MacKenzie, Duncan, Witherspoon, Luke, Osmond, Matthew, Holcik, Martin, MacKenzie, Alex
Publicerad 2011

Motoneuron Resistance to Apoptotic Cell Death In Vivo Correlates with the Ratio between X-Linked Inhibitor of Apoptosis Proteins (XIAPs) and Its Inhibitor, XIAP-Associated Factor 1

av Perrelet, Daniel, Perrin, Florence E., Liston, Peter, Korneluk, Robert G., MacKenzie, Alex, Ferrer-Alcon, Marcel, Kato, Ann C.
I publikationen J Neurosci (2004)

High-throughput DNA Extraction and Genotyping of 3dpf Zebrafish Larvae by Fin Clipping

av Kosuta, Ceres, Daniel, Kate, Johnstone, Devon L., Mongeon, Kevin, Ban, Kevin, LeBlanc, Sophie, MacLeod, Stuart, Et-Tahiry, Karim, Ekker, Marc, MacKenzie, Alex, Pena, Izabella
I publikationen J Vis Exp (2018)

The Neuronal Apoptosis Inhibitory Protein Is a Direct Inhibitor of Caspases 3 and 7

av Maier, Johannes K. X., Lahoua, Zahia, Gendron, Nathalie H., Fetni, Raouf, Johnston, Anne, Davoodi, Jamshid, Rasper, Dita, Roy, Sophie, Slack, Ruth S., Nicholson, Donald W., MacKenzie, Alex E.
I publikationen J Neurosci (2002)

A generalizable pre-clinical research approach for orphan disease therapy

av Beaulieu Chandree L, Samuels Mark E, Ekins Sean, McMaster Christopher R, Edwards Aled M, Krainer Adrian R, Hicks Geoffrey G, Frey Brendan J, Boycott Kym M, MacKenzie Alex E
Publicerad 2012-06-01

A generalizable pre-clinical research approach for orphan disease therapy

av Beaulieu, Chandree L, Samuels, Mark E, Ekins, Sean, McMaster, Christopher R, Edwards, Aled M, Krainer, Adrian R, Hicks, Geoffrey G, Frey, Brendan J, Boycott, Kym M, MacKenzie, Alex E
Publicerad 2012

The human ryanodine receptor gene: Its mapping to 19q13.1, placement in a chromosome 19 linkage group, and exclusion as the gene causing myotonic dystrophy

av MacKenzie, Alex E., Korneluk, Robert G., Zorzato, Francesco, Fujii, Junichi, Phillips, Michael, Iles, David, Wieringa, Bé, Leblond, Suzanne, Bailly, Jane, Willard, Huntington F., Duff, Catherine, Worton, Ronald G., MacLennan, David H.
Publicerad 1990

Inhibitor of apoptosis proteins, NAIP, cIAP1 and cIAP2 expression during macrophage differentiation and M1/M2 polarization

av Morón-Calvente, Virginia, Romero-Pinedo, Salvador, Toribio-Castelló, Sofía, Plaza-Díaz, Julio, Abadía-Molina, Ana C., Rojas-Barros, Domingo I., Beug, Shawn T., LaCasse, Eric C., MacKenzie, Alex, Korneluk, Robert, Abadía-Molina, Francisco
I publikationen PLoS One (2018)