Novel Cryo-EM structures of the D1 dopamine receptor unlock its therapeutic potential

af Sibley, David R., Luderman, Kathryn D., Free, R. Benjamin, Shi, Lei
Udgivet i Signal Transduct Target Ther (2021)

Protein Kinase C Beta Regulates the D2-Like Dopamine Autoreceptor

af Luderman, Kathryn D., Chen, Rong, Ferris, Mark J., Jones, Sara R., Gnegy, Margaret E.
Udgivet i Neuropharmacology (2015)

Leptin promotes dopamine transporter and tyrosine hydroxylase activity in the nucleus accumbens of Sprague-Dawley rats

af Perry, Maura L., Leinninger, Gina M., Chen, Rong, Luderman, Kathryn D., Yang, Hongyan, Gnegy, Margaret E., Myers, Martin G., Kennedy, Robert T.
Udgivet 2010

An N-Terminal Threonine Mutation Produces an Efflux-Favorable, Sodium-Primed Conformation of the Human Dopamine Transporter

af Fraser, Rheaclare, Chen, Yongyue, Guptaroy, Bipasha, Luderman, Kathryn D., Stokes, Stephanie L., Beg, Asim, DeFelice, Louis J., Gnegy, Margaret E.
Udgivet 2014

A Mechanism Linking Two Known Vulnerability Factors for Alcohol Abuse: Heightened Alcohol Stimulation and Low Striatal Dopamine D2 Receptors

af Bocarsly, Miriam E., da Silva e Silva, Daniel, Kolb, Vanessa, Luderman, Kathryn D., Shashikiran, Sannidhi, Rubinstein, Marcelo, Sibley, David R., Dobbs, Lauren K., Alvarez, Veronica A.
Udgivet i Cell Rep (2019)

Identification of Positive Allosteric Modulators of the D(1) Dopamine Receptor That Act at Diverse Binding Sites

af Luderman, Kathryn D., Conroy, Jennie L., Free, R. Benjamin, Southall, Noel, Ferrer, Marc, Sanchez-Soto, Marta, Moritz, Amy E., Willette, Blair K. A., Fyfe, Tim J., Jain, Prashi, Titus, Steve, Hazelwood, Lisa A., Aubé, Jeffrey, Lane, J. Robert, Frankowski, Kevin J., Sibley, David R.
Udgivet i Mol Pharmacol (2018)